Compare Hemodynamic Parameters of Propofol and Sevoflurane During CPB Time in Undergoing CABG to Avoid Lactate Level

NCT ID: NCT05004545

Last Updated: 2021-08-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

126 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-06-10

Study Completion Date

2021-12-30

Brief Summary

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Hemodynamic parameters and lactate level will be on CBP during CABG surgery patients.

Detailed Description

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Objective: To compare hemodynamic parameters of propofol and sevoflurane during cardiopulmonary bypass time in patients undergoing coronary artery bypass graft (CABG) surgery to avoid lactate level.

Methods: One hundred and twenty six patients scheduled for CABG from May 2017 to May 2018 will be included in this study. Non probability consecutive sampling will be used. Patients will be divided in two groups, propofol will be given to group 1, and sevoflurane will be given to group 2. Age, clamp time, bypass time, mean arterial blood pressure on bypass machine and lactate level will be compared between two groups. SPSS version 24 will used and p value ≤ 0.05 will be considered as significant.

Conditions

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Hemodynamic Instability

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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group 1 Profol Infusion to CABG patients to check lactate level

Propofol infusion according to bodyweight will be given to check lactate level on CPB

Group Type EXPERIMENTAL

Propofol

Intervention Type DRUG

Propofol infusion according to body weight will be compared with sevoflurane acording to MAC % to see the lactate level and hemodynamic parameters of CABG patients

sevoflurane will be given to group 2 to check lacate level

Sevoflurane MAC % will be given to CABG patients to check lactate level

Group Type ACTIVE_COMPARATOR

Propofol

Intervention Type DRUG

Propofol infusion according to body weight will be compared with sevoflurane acording to MAC % to see the lactate level and hemodynamic parameters of CABG patients

Interventions

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Propofol

Propofol infusion according to body weight will be compared with sevoflurane acording to MAC % to see the lactate level and hemodynamic parameters of CABG patients

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

CABG

Exclusion Criteria

Emergency surgery
Minimum Eligible Age

20 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Chaudhry Pervaiz Elahi Institute of Cardiology

OTHER_GOV

Sponsor Role lead

Responsible Party

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Muhammad Imran Khan

Principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Kaneez Ume Farwa, FCPS

Role: PRINCIPAL_INVESTIGATOR

Chaudhry Pervaiz Elahi Institute of Cardiology

Locations

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Cardiac Surgery ICU

Multan, Punjab Province, Pakistan

Site Status RECRUITING

Countries

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Pakistan

Central Contacts

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Kaneez Ume Farwa, FCPS

Role: CONTACT

+923356787214

Facility Contacts

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Kneez Ume Farwa, FCPS

Role: primary

Other Identifiers

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CPEIC-06

Identifier Type: -

Identifier Source: org_study_id

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