Ciprofol Versus Propofol for Anesthesia Induction in Cardiac Surgery: A Randomized Double-blind Controlled Clinical Trial

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-03-11

Study Completion Date

2024-05-10

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Ciprofol, a novel intravenous general anesthetic with a chemical structure akin to propofol, boasts significantly enhanced potency. It offers a rapid onset, reduced incidence of injection pain, and minor impact on the cardiovascular system. However, clinical research regarding ciprofol's use for anesthesia induction in cardiac surgery remains limited.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Safety and Effectiveness of Ciprofol in Cardiac Surgery Anesthesia

NCT05892471

Anesthesia

UNKNOWN NA

Clinical Observation of Ciprofol for Anesthesia Induction

NCT05706337

Anesthesia Pain Hemodynamic Instability

UNKNOWN PHASE4

Comparison of Ciprofol-based and Propofol-based Total Intravenous Anesthesia on Postoperative Quality of Recovery

NCT05843383

Anesthetics, Intravenous Postoperative Complications Hypnotics and Sedatives +1 more

UNKNOWN NA

Ciprofol Versus Propofol for Tracheal Intubation in ICU

NCT06344949

Emergency Tracheal Intubation in Critically Ill Patients

COMPLETED PHASE4

Effect of Ciprofol Infusion for Induction and Maintenance on Hemodynamics and Postoperative Recovery

NCT05664386

Hemodynamics Postoperative Recovery Anesthesia

RECRUITING PHASE4

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Anesthesia

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Experimental: ciprofol

Group Type EXPERIMENTAL

Drug: ciprofol injection

Intervention Type DRUG

Patients in ciprofol group 0.3 mg/kg ciprofol for induction of anesthesia

Placebo Comparator: propofol

Group Type PLACEBO_COMPARATOR

Drug: ciprofol injection

Intervention Type DRUG

Patients in ciprofol group 0.3 mg/kg ciprofol for induction of anesthesia

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Drug: ciprofol injection

Patients in ciprofol group 0.3 mg/kg ciprofol for induction of anesthesia

Intervention Type DRUG

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

1. Elective surgery patients
2. Aged 55 to 75
3. New York Heart Association class II or III cardiac functions
4. Median sternotomy approach for coronary artery bypass grafting or heart valve replacement procedures

Exclusion Criteria

1. With a history of benzodiazepine allergy
2. Significant liver or kidney insufficiency
3. Coagulation dysfunction
4. Neurological or psychiatric disorders
5. Undergone major surgery within the past three months.

Minimum Eligible Age

55 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No