Single Lung Ventilation Versus Two Lung Ventilation

NCT ID: NCT04981990

Last Updated: 2021-08-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-03-01

Study Completion Date

2021-08-25

Brief Summary

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Hypoxia in single lung ventilation versus two lung ventilation in video assisted lung surgeries

Detailed Description

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Incidence of hypoxia in single lung ventilation by double lumen endotracheal tube "of choice in lung surgeries" versus incidence of hypoxia in two lung ventilation by conventional single lumen endotracheal tube "intermittent two lung ventilation"

Conditions

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Hypoxemia Single Lung Ventilation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Two equal groups: the first group undergoing lung surgeries with single lung ventilation by double lumen endotracheal tube, the second group undergoing lung surgeries with two lung ventilation using conventional single lumen endotracheal tube
Primary Study Purpose

OTHER

Blinding Strategy

SINGLE

Participants
The patients will not know whether they are in the first or second group

Study Groups

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Single lung ventilation

Using double lumen endotracheal tube and lung isolation

Group Type ACTIVE_COMPARATOR

Single lung ventilation by double lumen endotracheal tube

Intervention Type PROCEDURE

Single lung ventilation using double lumen endotracheal tube and isolation of the operated lung during surgery to create ideal surgical field

Two lung ventilation

Using conventional single lumen endotracheal tube and intermittent two lung ventilation

Group Type ACTIVE_COMPARATOR

Two lung ventilation by conventional single lumen endotracheal tube

Intervention Type PROCEDURE

Intermittent two lung ventilation so that no significant hypoxia occurs with creating optimum surgical field

Interventions

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Single lung ventilation by double lumen endotracheal tube

Single lung ventilation using double lumen endotracheal tube and isolation of the operated lung during surgery to create ideal surgical field

Intervention Type PROCEDURE

Two lung ventilation by conventional single lumen endotracheal tube

Intermittent two lung ventilation so that no significant hypoxia occurs with creating optimum surgical field

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Age group: Adult patients from age of 21 years to 60 years
* Sex: Both sexes
* ASA Classification: patients with ASA classification II, III.
* Elective lung surgeries using video assisted thoracoscopic surgeries.

Exclusion Criteria

* Patients refuse to give informed consent.
* ASA Classification: ASA IV.
* Failure of thoracoscopic surgeries and continue as open thoracotomy
* Patients with ischemic heart diseases, where hypoxemia might be preexisting, or patient be more vulnerable to hypoxemia whatever the technique or time of hypoxia.
* Emergency lung surgeries.
* Patients underwent previous lung surgeries of any cause.
* Patients with pathology to the non-operated side.
Minimum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ain Shams University

OTHER

Sponsor Role lead

Responsible Party

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Esraa Abdellatif

Anesthesia resident, principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Esraa Abdellatif, M.B., B.Ch.

Role: PRINCIPAL_INVESTIGATOR

Anesthesiology department

Omar El safty, MD

Role: STUDY_CHAIR

Anesthesiology department

Salwa Omar, MD

Role: STUDY_DIRECTOR

Anesthesiology department

Mohamed Taeimah, MD

Role: STUDY_DIRECTOR

Anesthesiology department

Locations

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Aun Shams University Hospitals

Cairo, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Esraa Abdellatif

Role: CONTACT

01119895491

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Document Type: Informed Consent Form

View Document

Other Identifiers

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Anesth

Identifier Type: -

Identifier Source: org_study_id

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