The Effects of Three Different Ultrasound-guided Nerve Blocks in VATS

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-04-05

Study Completion Date

2022-12-31

Brief Summary

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Ultrasound-guided mid-point transverse process to pleura block, erector spinae plane block and paravertebral block are three different methods of nerve block, used for relieving postoperative pain in thoracic anesthesia. This study is to compare them on block effects, postoperative pain and analgesic consumption in video-assisted thoracic surgery.

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Detailed Description

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Ultrasound-guided nerve block is an important part of multi-mode analgesia to decrease the consumption of opioids. Thoracic paravertebral block is considered as an ideal regional analgesic choice for video-assisted thoracic surgery, but it still has some side effects, such as pneumothorax, vascular injury, especially for novices. Recent years, ultrasound-guided mid-point transverse process to pleura block and erector spinae plane block are reported for thoracic surgery. The insertion depth in these two methods is more superficial than traditional paravertebral block. They could have less side effects. Therefore, we design a randomised control study to compare them on block effects, postoperative pain and analgesic consumption in video-assisted thoracic surgery.

Conditions

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Thoracic Anesthesia Nerve Block Pain, Acute

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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paravertebral block

Patients receive ultrasound-guided paravertebral block

Group Type ACTIVE_COMPARATOR

Paravertebral block

Intervention Type PROCEDURE

Patients receive ultrasound-guided paravertebral block

ESP block

Patients receive ultrasound-guided erector spinae plane (ESP) block

Group Type ACTIVE_COMPARATOR

ESP block

Intervention Type PROCEDURE

Patients receive ultrasound-guided erector spinae plane (ESP) block

MTP block

Patients receive ultrasound-guided mid-point transverse process to pleura (MTP) block

Group Type EXPERIMENTAL

MTP block

Intervention Type PROCEDURE

Patients receive ultrasound-guided mid-point transverse process to pleura (MTP) block

Interventions

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Paravertebral block

Patients receive ultrasound-guided paravertebral block

Intervention Type PROCEDURE

ESP block

Patients receive ultrasound-guided erector spinae plane (ESP) block

Intervention Type PROCEDURE

MTP block

Patients receive ultrasound-guided mid-point transverse process to pleura (MTP) block

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* selective lobetomy under VATS
* ASA classfication 1-3

Exclusion Criteria

* history of thoracic surgery
* double lateral VATS
* allergy to local anesthetics
* coagulation disorders
* severe heart diseases, hepatic or renal insufficiency
* a history of chronic pain or chronic opioid use
* psychiatric disease or uncooperative
* BMI\>28 kg/m2
* VATS transfered to open thoractomy

Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No