Transverse Thoracic Plane Block, Midpoint Transverse Process Plane to Pleura Block and Erector Spinae Plane Block for Analgesia in Patients Undergoing Thoracoscopic Sympathectomy

NCT ID: NCT06987110

Last Updated: 2025-11-25

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 60 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2025-05-24
• Study Completion Date: 2025-10-11

Brief Summary

This study compares the transversus thoracic muscle plane block (TTPB), midtransverse to pleura block (MTPB), and erector spinae plane block (ESPB) for postoperative analgesia in patients undergoing thoracoscopic sympathectomy.

Detailed Description

Thoracoscopic sympathectomy is a well-established procedure for the treatment of various hyperhidrosis disorders and certain vascular conditions, involving the division of sympathetic nerve fibers in the thoracic cavity.

The erector spinae plane block (ESPB) is an interfascial regional anesthesia block for thoracic analgesia which can be performed by superficial or deep needle approach.

The mid-transverse to pleura block (MTPB) was first described as a modified paravertebral block.

Transversus thoracic muscle plane block (TTPB) is a newly developed technique in which LA is injected into the fascial plane between the transversus thoracic muscle and the internal intercostal muscles for blocking the anterior cutaneous branches of intercostal nerves from thoracic (Th) 2 to Th 6.

Conditions

Transverse Thoracic Plane Block; Midpoint Transverse Process Plane to Pleura Block; Erector Spinae Plane Block; Analgesia; Thoracoscopic Sympathectomy

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: DOUBLE

Study Groups

Transverse thoracic plane block group

Patients will receive a transverse thoracic plane block.

Group Type: EXPERIMENTAL

Transverse thoracic plane block

Intervention Type: OTHER

Patients will receive a transverse thoracic plane block.

Midpoint transverse process plane to pleura block group

Patients will receive a midpoint transverse process plane to pleura block.

Group Type: EXPERIMENTAL

Midpoint transverse process plane to pleura block

Intervention Type: OTHER

Patients will receive a midpoint transverse process plane to pleura block.

Erector spinae plane block group

Patients will receive an erector spinae plane block.

Group Type: EXPERIMENTAL

Erector spinae plane block

Intervention Type: OTHER

Patients will receive an erector spinae plane block.

Interventions

Midpoint transverse process plane to pleura block

Patients will receive a midpoint transverse process plane to pleura block.

Intervention Type: OTHER

Erector spinae plane block

Patients will receive an erector spinae plane block.

Intervention Type: OTHER

Transverse thoracic plane block

Patients will receive a transverse thoracic plane block.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Age from 18 to 65 years.
• Both sexes.
• American Society of Anesthesiology (ASA) physical status I-II.
• Scheduled for thoracoscopic sympathectomy

Exclusion Criteria

• Coagulopathy.
• History of opiate abuse.
• Pre-existing chronic pain.
• Allergy to local anesthetics or analgesics.
• Infection at the site of injection.
• Mental or neurological disorders.
• Pregnancy

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 65 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Tanta University

OTHER

Sponsor Role: lead

Responsible Party

Mahmoud Abdalsattar Elmohasseb

Lecturer of Anesthesiology, Surgical Intensive Care and Pain Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt.

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Tanta University

Tanta, El-Gharbia, Egypt

Countries

Egypt

Other Identifiers

36264PR1182/4/25.

Identifier Type: -

Identifier Source: org_study_id