Comparing Different Regional Blocks for Analgesia After Off-pump Cardiac Surgery

NCT ID: NCT05763810

Last Updated: 2025-05-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

22 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-03-15

Study Completion Date

2025-12-31

Brief Summary

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This study aims to compare the analgesic effects of erector spinae plane block versus Superficial Parasternal Intercostal Plane Block block along with rectus sheath block after off-pump cardiac surgery

Detailed Description

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General anaesthesia will be used for all patients. induction by midazolam 0.05-0.1 mg/kg, fentanyl 2-5 µ/kg, propofol 1-2 mg/kg, and atracurium 0.5 mg/kg for intubation. Maintenance by sevoflurane in oxygen-air mixture. regional blocks will be used after the induction of anaesthesia. Intraoperative analgesia will be maintained by fentanyl infusion 1-2 µ/kg/h while morphine sulphate 2.5-5mg will be used as rescue analgesia when pain score\>4 beside acetaminophen 1000 mg /6 hours

Conditions

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Analgesia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Erector Spinae Plane Block group

Erector Spinae Plane Block

Group Type OTHER

Erector Spinae Plane Block

Intervention Type OTHER

Erector Spinae Plane Block

Superficial Parasternal Intercostal Plane Block and Rectus Sheath Block group

Superficial Parasternal Intercostal Plane Block and Rectus Sheath Block

Group Type OTHER

Superficial Parasternal Intercostal Plane Block combined with Rectus Sheath Block

Intervention Type OTHER

Superficial Parasternal Intercostal Plane Block combined with Rectus Sheath Block

Interventions

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Erector Spinae Plane Block

Erector Spinae Plane Block

Intervention Type OTHER

Superficial Parasternal Intercostal Plane Block combined with Rectus Sheath Block

Superficial Parasternal Intercostal Plane Block combined with Rectus Sheath Block

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* American Society of anaesthesiologists physical status classification II-III
* Elective off-pump cardiac surgery

Exclusion Criteria

* Cognitive impairment
* Allergy to local anaesthetics
* Renal and/or hepatic dysfunction
* Ejection fraction\< 45%
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Abd-Elazeem Abd-Elhameed Elbakry

OTHER

Sponsor Role lead

Responsible Party

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Abd-Elazeem Abd-Elhameed Elbakry

Professor

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Abd-Elazeem A Elbakry, MD

Role: PRINCIPAL_INVESTIGATOR

Menoufia University

Amal G Safan, MD

Role: PRINCIPAL_INVESTIGATOR

Menoufia University

Islam M El-Desoky, MD

Role: PRINCIPAL_INVESTIGATOR

Menoufia University

Locations

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Faculty of Medicine

Cairo, Shebin Elkom, Egypt

Site Status

Countries

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Egypt

Other Identifiers

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2/2023 ANET 15-3

Identifier Type: -

Identifier Source: org_study_id

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