Comparison of Superficial+Deep Vs. Deep Serratus Anterior Plan Block in Video-Assisted Thoracic Surgery

NCT ID: NCT05852561

Last Updated: 2024-04-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-05-15

Study Completion Date

2023-12-15

Brief Summary

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Thoracotomy is one of the most painful surgeries; Video-assisted thoracoscopic surgery (VATS) has been developed to reduce the surgical stress of thoracotomy. However, patients may experience moderate to severe pain within the first 24 hours after VATS. Intravenous opioids are frequently used to provide postoperative analgesia, and accordingly, side effects such as postoperative nausea/vomiting and respiratory depression can be seen.

The aim of this study is to compare Superficial+Deep Vs. Deep Serratus Anterior Plan Block for postoperative pain control in VATS cases.

Detailed Description

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Conditions

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Analgesia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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Group Superficial+Deep Serratus Anterior Plan Block

Superficial+Deep Serratus Anterior Plan Block after Video-Assisted Thoracic Surgery

Group Type ACTIVE_COMPARATOR

Group Superficial+Deep Serratus Anterior Plan Block

Intervention Type OTHER

The block will be performed after induction of general anesthesia and surgical positioning. 15 ml of 0.375% Bupivacaine + epinephrine 5 µg/ml will be administered between the serratus anterior and latissimus dorsalis muscles. The same concentration of block fluid will be applied between the serratus anterior and the outer intercostal muscle.

Group Deep Serratus Anterior Plan Block

Deep Serratus Anterior Plan Block after Video-Assisted Thoracic Surgery

Group Type ACTIVE_COMPARATOR

Group Deep Serratus Anterior Plan Block

Intervention Type OTHER

30 ml 0.375% Bupivacaine + epinephrine 5 µg/ml will be administered between the serratus anterior and outer intercostal muscle.

Interventions

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Group Superficial+Deep Serratus Anterior Plan Block

The block will be performed after induction of general anesthesia and surgical positioning. 15 ml of 0.375% Bupivacaine + epinephrine 5 µg/ml will be administered between the serratus anterior and latissimus dorsalis muscles. The same concentration of block fluid will be applied between the serratus anterior and the outer intercostal muscle.

Intervention Type OTHER

Group Deep Serratus Anterior Plan Block

30 ml 0.375% Bupivacaine + epinephrine 5 µg/ml will be administered between the serratus anterior and outer intercostal muscle.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. American Society of Anesthesiologist's physiologic state I-III patients
2. To undergo Video Assisted Thoracic Surgery
3. Being between the ages of 18-65 years

Exclusion Criteria

* having a known heart, kidney, liver or hematological disease
* having a history of peptic ulcer, gastrointestinal bleeding, allergy, chronic pain
* Routine analgesic use and history of analgesic use in the last 24 hours
* Not willingto participate in the study
* Uncooperative patients who have coagulopathy or use anticoagulant drugs
* To be allergic to one of the drugs to be used
* Contraindication for Video Assisted Thoracic Surgery
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ataturk University

OTHER

Sponsor Role lead

Responsible Party

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Elif Oral Ahiskalioglu

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Elif Oral Ahiskalioglu

Role: STUDY_DIRECTOR

Ataturk University

Locations

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Ali Ahiskalioglu

Erzurum, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Lee J, Kim S. The effects of ultrasound-guided serratus plane block, in combination with general anesthesia, on intraoperative opioid consumption, emergence time, and hemodynamic stability during video-assisted thoracoscopic lobectomy: A randomized prospective study. Medicine (Baltimore). 2019 May;98(18):e15385. doi: 10.1097/MD.0000000000015385.

Reference Type BACKGROUND
PMID: 31045789 (View on PubMed)

Qiu L, Bu X, Shen J, Li M, Yang L, Xu Q, Chen Y, Yang J. Observation of the analgesic effect of superficial or deep anterior serratus plane block on patients undergoing thoracoscopic lobectomy. Medicine (Baltimore). 2021 Jan 22;100(3):e24352. doi: 10.1097/MD.0000000000024352.

Reference Type BACKGROUND
PMID: 33546068 (View on PubMed)

Other Identifiers

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ataunivatsanalgesia

Identifier Type: -

Identifier Source: org_study_id

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