Effect of Different Local Anesthetic Volumes of Serratus Anterior Plan Block After Video-Assisted Thoracoscopic Surgery

NCT ID: NCT05255536

Last Updated: 2024-02-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-02-15

Study Completion Date

2024-05-15

Brief Summary

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Video-assisted thoracic surgery (VATS) has become a common procedure in thoracic surgery. Severe postoperative pain may be encountered in patients undergoing VATS. Analgesic methods such as thoracic paravertebral block (TPVB), intercostal block, serratus anterior plane block (SAPB), and erector spinae plane block (ESPB) are widely used for VATS. Among these methods, ultrasound (US) guided TPVB is the most preferred method. In recent years, the frequency of application of plane blocks as a component of multimodal analgesia has been increased. ESPB and SAPB are some of them. In addition, SAPB application is increasing in patients who underwent thoracotomy and VATS. There is no consensus on the dose of analgesia in these studies. There are studies on volumes between 10 ml and 40 ml in the literature. In this study, it was aimed to compare the volumes of 20 ml and 30 ml containing local anesthetic at the same concentration (0.25% bupivacaine) of SAPB block to be performed with USG in patients who underwent VATS.

Detailed Description

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Conditions

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Serratus Anterior Plane Block Pain, Postoperative Thoracic Surgery, Video-Assisted Local Anesthetic

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Serratus Anterior Plan Block with 20 ml %0.25 Bupivacaine

Following the visualization of the anatomical structures, the nerve block needle will be advanced via the in-plane technique above the serratus anterior muscles until the interfascial space was reached. After hydrodissection with 2 ml normal saline, 20 ml 0.25% bupivacaine will be injected into the area.

Group Type ACTIVE_COMPARATOR

Serratus Anterior Plan Block with 20 ml

Intervention Type PROCEDURE

Superficial serratus anterior plane block with 20 ml will be applied to the patients under real-time ultrasound guidance.

Serratus Anterior Plan Block with 30 ml %0.25 Bupivacaine

Following the visualization of the anatomical structures, the nerve block needle will be advanced via the in-plane technique above the serratus anterior muscles until the interfascial space was reached. After hydrodissection with 2 ml normal saline, 30 ml 0.25% bupivacaine will be injected into the area.

Group Type ACTIVE_COMPARATOR

Serratus Anterior Plan Block with 30 ml

Intervention Type PROCEDURE

Superficial serratus anterior plane block with 30 ml will be applied to the patients under real-time ultrasound guidance.

Interventions

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Serratus Anterior Plan Block with 20 ml

Superficial serratus anterior plane block with 20 ml will be applied to the patients under real-time ultrasound guidance.

Intervention Type PROCEDURE

Serratus Anterior Plan Block with 30 ml

Superficial serratus anterior plane block with 30 ml will be applied to the patients under real-time ultrasound guidance.

Intervention Type PROCEDURE

Other Intervention Names

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Drug Drug

Eligibility Criteria

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Inclusion Criteria

* 18 to 65 years old
* ASA physical status I-II-III
* BMI 18 to 30 kg/m2
* Elective video assisted thoracoscopic surgery

Exclusion Criteria

* Patient refusing the procedure
* Emergency surgery
* Chronic opioid or analgesic use
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Atatürk Chest Diseases and Chest Surgery Training and Research Hospital

OTHER

Sponsor Role lead

Responsible Party

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Musa Zengin

Principal İnvestigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Musa Zengin, MD

Role: PRINCIPAL_INVESTIGATOR

Atatürk Chest Diseases and Chest Surgery Training and Research Hospital

Locations

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Ankara Atatürk Chest Disease and Chest Surgery Training and Research Hospital

Keçiören, Ankara, Turkey (Türkiye)

Site Status RECRUITING

Countries

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Turkey (Türkiye)

Central Contacts

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Musa Zengin, MD

Role: CONTACT

903125677233

Ali Alagoz, Assoc Prof

Role: CONTACT

+903125677232

Facility Contacts

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Musa Zengin, MD

Role: primary

+903125677233

Other Identifiers

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E.Kurul-E1-22-2371

Identifier Type: -

Identifier Source: org_study_id

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