Comparison of Thoracic Paravertebral Block and Pectoral Nerve Block

NCT ID: NCT04855994

Last Updated: 2021-07-09

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 52 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2017-06-28
• Study Completion Date: 2018-08-28

Brief Summary

This study aims to compare the efficacy and safety of ultrasound-guidedPECS II block with TPVB for postoperative analgesia after VATS.

Detailed Description

52 patients (ASA I-III) between 18 and 65 years of age, who were to undergo VATS, were randomized and divided into two groups. (26 patients in each of the PECS and TPVB groups) Thoracic paravertebral block was administered from two consecutive levels for TPVB group and a modified pectoral nerve block was performed in the PECS group. Postoperative analgesia was provided by intravenous morphine infusion using a patient-controlled analgesia device. Postoperative 24-hour total morphine consumption and duration of analgesia were the primary outcome measure. Perioperative remifentanil use, visual analog scale values during at rest and coughing, time of the first analgesic request, and additional analgesic consumption were recorded.

Conditions

Thoracic Paravertebral Block; Video-assisted Thoracoscopic Surgery; Postoperative Analgesia

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: SUPPORTIVE_CARE
• Blinding Strategy: SINGLE

Study Groups

paravertebral group

The investigators performed Paravertebral block to that patient group for postoperative analgesia

Group Type: ACTIVE_COMPARATOR

paravertebral block

Intervention Type: PROCEDURE

The investigators performed Paravertebral block to that patient group for postoperative analgesia

pectoral group

The investigators performed pectoral block to that patient group for postoperative analgesia

Group Type: ACTIVE_COMPARATOR

pectoral block

Intervention Type: PROCEDURE

The investigators performed pectoral block to that patient group for postoperative analgesia

Interventions

paravertebral block

The investigators performed Paravertebral block to that patient group for postoperative analgesia

Intervention Type: PROCEDURE

pectoral block

The investigators performed pectoral block to that patient group for postoperative analgesia

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• Ages of 18-65
• Patients who will undergo VATS
• ASA I-II-III patients

Exclusion Criteria

• Patients with ASA IV
• Clinically diagnosis of spinal or chest wall deformity or pathology
• Clinically known local anesthetic allergy
• Morbid obesity (body mass index>40 kg m2)
• Clinically diagnosis of opioid, alcohol and substance dependence
• Clinically diagnosis of psychiatric disease
• Coagulopathy

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 65 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Bakirkoy Dr. Sadi Konuk Research and Training Hospital

OTHER_GOV

Sponsor Role: lead

Responsible Party

Gokhan Sertcakacilar, MD

Principal Investigator, MD

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Gokhan Sertcakacilar, MD

Role: STUDY_DIRECTOR

Bakirkoy Dr. Sadi Konuk Research and Training Hospital

Locations

Bakirkoy Dr. Sadi Konuk Research and Training Hospital

Istanbul, Bakirkoy, Turkey (Türkiye)

Countries

Turkey (Türkiye)

Other Identifiers

2017-140

Identifier Type: -

Identifier Source: org_study_id