Transversus Thoracic Muscle Plane Block, Erector Spinae Plane Block and Paravertebral Block for Analgesia in Video-Assisted Thoracic Surgery

NCT ID: NCT06987136

Last Updated: 2025-11-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-05-24

Study Completion Date

2025-11-08

Brief Summary

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The aim of this study is to compare the transversus thoracic muscle plane block (TTPB), erector spinae plane block (ESPB), and thoracic paravertebral block (TPVB) for postoperative analgesia in patients undergoing video-assisted thoracoscopic surgery (VATS).

Detailed Description

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Traditionally, resection is done via a thoracotomy. Still, video-assisted thoracoscopic surgery (VATS) provides significant advantages over open thoracotomy procedures, including reduced surgical pain, improved postoperative pulmonary function, reduced mortality, shortened hospital stay. It has emerged as a minimally invasive alternative.

Thoracic paravertebral block (TPVB) is a regional anesthetic technique in which local anesthetic (LA) is administered inside the thoracic paravertebral space (TPVS), which contains the intercostal spinal nerves, spinal dorsal rami, rami communicants, sympathetic chain, intercostal vessels, and fatty tissue.

The erector spinae plane block (ESPB) is an interfascial regional anesthesia block for thoracic analgesia which can be performed by superficial or deep needle approach.

Transversus thoracic muscle plane block (TTPB) is a newly developed technique in which LA is injected into the fascial plane between the transversus thoracic muscle and the internal intercostal muscles for blocking the anterior cutaneous branches of intercostal nerves from thoracic (Th) 2 to Th 6.

Conditions

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Transversus Thoracic Muscle Plane Block Erector Spinae Plane Block Paravertebral Block Analgesia Video-Assisted Thoracic Surgery

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Transversus thoracic muscle plane block group

Patients will receive a transversus thoracic muscle plane block.

Group Type EXPERIMENTAL

Transversus thoracic muscle plane block

Intervention Type OTHER

Patients will receive a transversus thoracic muscle plane block.

Erector spinae plane block group

Patients will receive an erector spinae plane block.

Group Type EXPERIMENTAL

Erector spinae plane block

Intervention Type OTHER

Patients will receive an erector spinae plane block.

Thoracic paravertebral block group

Patients will receive a thoracic paravertebral block.

Group Type EXPERIMENTAL

Thoracic paravertebral block

Intervention Type OTHER

Patients will receive a thoracic paravertebral block.

Interventions

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Transversus thoracic muscle plane block

Patients will receive a transversus thoracic muscle plane block.

Intervention Type OTHER

Erector spinae plane block

Patients will receive an erector spinae plane block.

Intervention Type OTHER

Thoracic paravertebral block

Patients will receive a thoracic paravertebral block.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age ≥ 18 years.
* Both sexes.
* American Society of Anesthesiology (ASA) physical status I-II.
* Scheduled for video-assisted thoracic surgery under general anesthesia.

Exclusion Criteria

* Body mass index \>30 kg/m2.
* Coagulopathy.
* History of opiate abuse.
* Pre-existing chronic pain.
* Allergy to local anesthetics or analgesics.
* Infection at the site of injection.
* Mental or neurological disorders.
* Operation converted to open thoracotomy.
* Renal dysfunction (glomerular filtration rate (GFR) \< 50 ml/min).
* Pregnancy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Tanta University

OTHER

Sponsor Role lead

Responsible Party

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Mahmoud Abdalsattar Elmohasseb

Lecturer of Anesthesiology, Surgical Intensive Care and Pain Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Tanta University

Tanta, El-Gharbia, Egypt

Site Status

Countries

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Egypt

Other Identifiers

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36264PR1184/4/25.

Identifier Type: -

Identifier Source: org_study_id

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