External Oblique Intercostal Plane Block Versus Thoracic Paravertebral Block for Post Thoracotomy Pain

NCT ID: NCT06431880

Last Updated: 2025-08-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-05-30

Study Completion Date

2025-06-01

Brief Summary

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The aim of this study is to compare the effectiveness of analgesia achieved by external oblique intercostal plane block (EOIPB)and thoracic paravertebral block (TPVB) for postoperative pain management in patients undergoing open thoracotomy.

Detailed Description

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Acute thoracotomy pain is multifactorial in nature. It involves nociceptive and neuropathic mechanisms originating from somatic and visceral afferents. The main sources of pain are intercostal nerves, the vagus nerve and phrenic nerve in the pleura, the superficial cervical plexus, and the brachial plexus in the ipsilateral shoulder.

Conditions

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External Oblique Intercostal Plane Block Thoracic Paravertebral Block Post Thoracotomy Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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External oblique intercostal plane block

Patients will receive external oblique intercostal plane block.

Group Type EXPERIMENTAL

External oblique intercostal plane block

Intervention Type OTHER

Patients will receive external oblique intercostal plane block

Thoracic paravertebral block

Patients will receive thoracic paravertebral block.

Group Type EXPERIMENTAL

Thoracic paravertebral block

Intervention Type OTHER

Patients will receive thoracic paravertebral block

Interventions

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External oblique intercostal plane block

Patients will receive external oblique intercostal plane block

Intervention Type OTHER

Thoracic paravertebral block

Patients will receive thoracic paravertebral block

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age ≥ 18 years.
* Both sexes.
* American Society of Anesthesiology (ASA) physical status I-III.
* Scheduled for open thoracotomy

Exclusion Criteria

* Patients with neurological or intellectual disability.
* Infection at the injection site.
* Opioid addiction.
* Allergic reaction to local anesthetics.
* Coagulation abnormalities.
* Drug abuse.
* Pregnancy.
* Severe liver and/or renal failure.
* Uncontrolled hypertension.
* Severe cardiovascular problems.
* Diabetes mellitus.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Tanta University

OTHER

Sponsor Role lead

Responsible Party

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Mohammed Said ElSharkawy

Lecturer of Anesthesiology, Surgical Intensive Care and Pain Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Tanta University Hospitals

Tanta, El-Gharbia Governorate, Egypt, Egypt

Site Status

Countries

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Egypt

Other Identifiers

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36246PR638/4/24

Identifier Type: -

Identifier Source: org_study_id

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