External Oblique Intercostal Plane Block Versus Transversus Abdominis Plane Block for Postoperative Analgesia in Adult Patients Undergoing Open Nephrectomy

NCT ID: NCT06452238

Last Updated: 2025-11-25

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 40 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2024-06-12
• Study Completion Date: 2025-10-22

Brief Summary

The aim of this study is to compare external oblique intercostal plane (EOIP) block and ultrasound guided transversus abdominis plane (TAP) Block for postoperative analgesia in adult patients undergoing open nephrectomy.

Detailed Description

Patients undergoing nephrectomy have a high incidence of postoperative pain despite the use of modern laparoscopic surgical techniques. In the postoperative period, these patients are often treated with patient-controlled opioids, epidural analgesia, or both.

Ultrasound-guided transversus abdominis plane (TAP) block is a relatively new technique to infiltrate regional anesthesia in which local routine anesthetics are injected between the internal oblique and transverse abdominal muscles. Studies have confirmed that ultrasound-guided (USG) transversus abdominis plane (TAP) block is an effective method of analgesia for upper abdominal surgeries, lower abdominal surgeries, and kidney transplantation, with minimal side effects.

External oblique intercostal plane block (EOIPB) has been reported by Elsharkawy et al. in 2021 as a significant modification of fascial plane blocks in that it may engage the upper lateral abdominal walls consistently. In comparison to quadratus lumborum block (QLB) and erector spinae plane block (ESPB) , The advantage of EOIPB is that it may be performed with the patient supine. Furthermore, in comparison to serratus intercostal plane block (SIPB), it generates more extensive analgesic effects throughout the whole midline of the abdomen .

Conditions

External Oblique Intercostal Plane Block; Transversus Abdominis Plane Block; Postoperative Analgesia; Nephrectomy

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: DOUBLE

Study Groups

External Oblique Intercostal Plane Block

Patients will receive external oblique intercostal plane block .

Group Type: EXPERIMENTAL

External Oblique Intercostal Plane Block

Intervention Type: OTHER

Patients will receive external oblique intercostal plane block .

Transversus Abdominis Plane Block

Patients will receive ultrasound guided transversus abdominis plane block.

Group Type: EXPERIMENTAL

Transversus Abdominis Plane Block

Intervention Type: OTHER

Patients will receive ultrasound-guided transversus abdominis plane block.

Interventions

External Oblique Intercostal Plane Block

Patients will receive external oblique intercostal plane block .

Intervention Type: OTHER

Transversus Abdominis Plane Block

Patients will receive ultrasound-guided transversus abdominis plane block.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Age ≥ 18 years.
• Both sexes.
• American Society of Anesthesiology (ASA) physical status I-II.
• Scheduled for open nephrectomy.

Exclusion Criteria

• Bleeding disorders.
• Skin lesions or infection at the site of proposed needle insertion.
• Allergy to local anesthetics.
• Neurological disorders.
• Drug abuse.
• BMI > 30 kg/m2.
• Pregnancy.
• Diabetic neuropathy.
• Severe cardiovascular problems.

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Tanta University

OTHER

Sponsor Role: lead

Responsible Party

Mohammed Said ElSharkawy

Lecturer of Anesthesiology, Surgical Intensive Care and Pain Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt.

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Tanta University

Tanta, El-Gharbia, Egypt

Countries

Egypt

Other Identifiers

36264PR639/4/24

Identifier Type: -

Identifier Source: org_study_id