Role of Ultrasound Guided Transversus Abdominis Plane Block in Pain Control After Hepatectomy

NCT ID: NCT06224179

Last Updated: 2024-01-30

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Clinical Phase: NA
• Total Enrollment: 40 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2024-02-01
• Study Completion Date: 2024-06-01

Brief Summary

Inadequately managed acute pain following abdominal surgery originates from somatic pain signals in the abdominal wall and is linked to various unfavorable postoperative outcomes. These consequences encompass patient distress, respiratory complications, delirium, myocardial ischemia, extended hospital stays, an elevated risk of chronic pain, heightened analgesic consumption, delayed bowel function, and an increased need for rescue analgesics.

This study aims to assess the postoperative analgesic efficacy of ultrasound-guided Transversus Abdominis Plane (TAP) block using oblique subcostal and posterior approaches in hepatectomy.

Detailed Description

Pain control is vital to achieve enhanced recovery after abdominal surgeries . TAP block had been demonstrated to improve pain related outcomes after abdominal surgeries.

Postoperative pain management for patients undergoing hepatic resection is a challenge due to the risk of perioperative liver dysfunction.TAP block is a promising regional analgesic technique. This study aimed to evaluate the effect of US-guided subcostal approach versus combination of both subcostal and posterior approaches of TAP block

The patients will be randomly divided into two groups :

group A will recieve oblique subcostal TAP block and group B will recieve both subcostal and posterior TAP block .

Conditions

Analgesia

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: PREVENTION
• Blinding Strategy: QUADRUPLE

Study Groups

Group A

Group A received ultrasound guided subcostal TAP block with 30 ml of local anesthetics and additives

Group Type: EXPERIMENTAL

ultrasound guided subcostal TAP block

Intervention Type: PROCEDURE

patients will be randomly divided into two groups using a computer generated random number chart.

Group A received ultrasound guided subcostal TAP block,

Group B

Group B received ultrasound guided both subcostal and posterior TAP block with 30 ml of local anesthetics and additives at each side

Group Type: EXPERIMENTAL

ultrasound guided combined posterior and subcostal TAP block

Intervention Type: PROCEDURE

patients will be randomly divided into two groups using a computer generated random number chart.

Group B received ultrasound guided combined posterior and subcostal TAP block,

Interventions

ultrasound guided subcostal TAP block

patients will be randomly divided into two groups using a computer generated random number chart.

Group A received ultrasound guided subcostal TAP block,

Intervention Type: PROCEDURE

ultrasound guided combined posterior and subcostal TAP block

patients will be randomly divided into two groups using a computer generated random number chart.

Group B received ultrasound guided combined posterior and subcostal TAP block,

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• ASA I and II patients. aged 18 to 50 years. 70 to 80 kg.

Exclusion Criteria

• patients under 18 years of age.

• History of Allergic reactions to study drugs.
• Opioid or analgesic abuse, and chronic treatment with opioids, or non-steroidal anti-inflammatory drugs.
• History of bleeding tendency or coagulopathy .

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 50 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Ain Shams University

OTHER

Sponsor Role: lead

Responsible Party

Ahmed wagih Ezzat deusouky

lecturer of anesthesia

Responsibility Role: PRINCIPAL_INVESTIGATOR

Central Contacts

Ahmed El-Dolah, lecturer of Anesthesia

Role: CONTACT

a_wagih82@yahoo.com

+20111113077

Other Identifiers

M S 96/2021

Identifier Type: -

Identifier Source: org_study_id