Transversus Abdominis Plane Block Versus External Oblique Intercostal Plane Block for Postoperative Analgesia in Pediatrics Undergoing Open Nephrectomy

NCT ID: NCT06452225

Last Updated: 2025-11-25

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 40 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2024-06-12
• Study Completion Date: 2025-10-20

Brief Summary

The aim of this study is to compare the ultrasound guided TAP Block and EOIP block for postoperative analgesia in pediatrics undergoing open nephrectomy.

Detailed Description

Nephrectomy in children may also be for malignant conditions of the kidney and adrenal glands. The major indications for nephrectomy vary in different parts of the world and in different age groups and sexes with some recording more benign conditions and others more of malignancies Ultrasound-guided transversus abdominis plane (TAP) block is a relatively new technique to infiltrate regional anesthesia in which local routine anesthetics are injected between the internal oblique and transverse abdominal muscles. The purpose is to provide analgesia to the parietal peritoneum as well as the skin and muscles of the anterior abdominal wall.

External oblique intercostal plane block (EOIPB) has been reported by Elsharkawy et al. in 2021 as a significant modification of fascial plane blocks in that it may engage the upper lateral abdominal walls consistently. In comparison to quadratus lumborum block (QLB) and erector spinae plane block (ESPB) , The advantage of EOIPB is that it may be performed with the patient supine. Furthermore, in comparison to serratus intercostal plane block (SIPB), it generates more extensive analgesic effects throughout the whole midline of the abdomen .

Conditions

Transversus Abdominis Plane Block; External Oblique Intercostal Plane Block; Postoperative Analgesia; Pediatrics; Open Nephrectomy

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: PREVENTION
• Blinding Strategy: DOUBLE

Study Groups

External Oblique Intercostal Plane Block

Patients will receive external oblique intercostal plane block.

Group Type: EXPERIMENTAL

External Oblique Intercostal Plane Block

Intervention Type: OTHER

Patients will receive external oblique intercostal plane block.

Transversus Abdominis Plane Block

Patients will receive ultrasound guided transversus abdominis plane block.

Group Type: EXPERIMENTAL

Transversus Abdominis Plane Block

Intervention Type: OTHER

Patients will receive ultrasound guided transversus abdominis plane block.

Interventions

External Oblique Intercostal Plane Block

Patients will receive external oblique intercostal plane block.

Intervention Type: OTHER

Transversus Abdominis Plane Block

Patients will receive ultrasound guided transversus abdominis plane block.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Age ≤ 18 years.
• Both sexes.
• American Society of Anesthesiology (ASA) physical status I-III.
• Scheduled for open nephrectomy.

Exclusion Criteria

• Abnormal blood coagulation.
• Scar, infection, and tumor of puncture site.
• History or family history of high malignant fever.
• Severe cardiovascular problems.

• Maximum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Tanta University

OTHER

Sponsor Role: lead

Responsible Party

Mohammed Said ElSharkawy

Lecturer of Anesthesiology, Surgical Intensive Care and Pain Medicine, Faculty of Medicine, Tanta University, Tanta, Egypt.

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Tanta University

Tanta, El-Gharbia, Egypt

Countries

Egypt

Other Identifiers

36264PR641/4/24

Identifier Type: -

Identifier Source: org_study_id