TEA, ESB and Paravertebral Block During Single-lung Ventilation for Lung Resection

NCT ID: NCT05211791

Last Updated: 2023-05-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-01-10

Study Completion Date

2023-10-20

Brief Summary

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Thoracotomy operations are known to be painful surgical procedures, so providing effective intraoperative and postoperative analgesia is so important for all anaesthesiologists. Ineffective pain management interferes with deep breathing, coughing, and remobilization resulting in atelectasis and pneumonia.

Ultrasound-guided ESP block is a myofascial plane block that provides analgesia for thoracic or abdominal segmental innervation depending on the level of the injection site. Thoracic epidural analgesia (TEA) is considered the gold standard analgesic technique for thoracic surgeries. But the invasiveness of this technique, the rare but serious neurologic complications and the failure rates up to 30% are the disadvantages of epidural analgesia

Detailed Description

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The aim of this study is to compare the effect of different blocks as TEA, erector spinae block or paravertebral block on improving peri-operative analgesia and post-operative outcome in pulmonary resection in adult patients.

Conditions

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Lung Diseases Pain, Acute

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

TRIPLE

Participants Caregivers Outcome Assessors

Study Groups

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Group TEA

insertion of Thoracic epidural anesthesia plus GA with lung isolation using suitable size double lumen tube at level T6

Group Type ACTIVE_COMPARATOR

Thoracic epidural anesthesia

Intervention Type PROCEDURE

insertion of Thoracic epidural catheter for anesthesia analgesia at level of T6

Group ESB

U/S guided erector spinae block anesthesia using 15 ml local anesthesia plus GA with lung isolation using a suitable size double-lumen tube

Group Type ACTIVE_COMPARATOR

erector spinae block

Intervention Type PROCEDURE

Ultrasound-guided insertion of different analgesic procedures as paravertebral block anesthesia and paravertebral block anesthesia

Group PVB

U/S guided paravertebral block anesthesia using 15 ml local anesthesia as total volume plus GA with lung isolation using suitable size double lumen tube

Group Type ACTIVE_COMPARATOR

paravertebral block anesthesia

Intervention Type PROCEDURE

Ultrasound-guided insertion of different analgesic procedures as paravertebral block anesthesia and paravertebral block anesthesia

Interventions

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erector spinae block

Ultrasound-guided insertion of different analgesic procedures as paravertebral block anesthesia and paravertebral block anesthesia

Intervention Type PROCEDURE

paravertebral block anesthesia

Ultrasound-guided insertion of different analgesic procedures as paravertebral block anesthesia and paravertebral block anesthesia

Intervention Type PROCEDURE

Thoracic epidural anesthesia

insertion of Thoracic epidural catheter for anesthesia analgesia at level of T6

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* aged between 18 to 70 years old for elective lung resection. with American Society of Anesthesiology physical status (ASA-PS) I-III

Exclusion Criteria

* Total pneumonectomy
* Hepatic or renal dysfunction.
* contraindications for epidural anesthesia as Coagulopathy and neurological and spinal deficits.
* emergency cases
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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South Egypt Cancer Institute

OTHER

Sponsor Role lead

Responsible Party

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Alaa Ali M. Elzohry

Lecturer of Anesthesia, ICU and Pain Relief, South Egypt Cancer Institute, Assiut University, Egypt

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Alaa A Elzohry

Role: PRINCIPAL_INVESTIGATOR

Lecturer of Anesthesia , ICU and pain management

Locations

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South Egypt Cancer Institute, Assiut University, Arab Republic of Egypt

Asyut, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Alaa A Elzohry, MD

Role: CONTACT

+201007356462

Facility Contacts

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Alaa A. Elzohry, MD

Role: primary

+2001007356462

Other Identifiers

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TEA in single lung ventilation

Identifier Type: -

Identifier Source: org_study_id

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