Shift Work Health Effects

NCT ID: NCT04813536

Last Updated: 2021-03-24

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 108 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2021-06-30
• Study Completion Date: 2022-12-31

Brief Summary

To identify the health effects of shift work on nurses in Assuit university hospitals .

To estimate effect of shift work on co-morbidities among nurses . To determine the shift work associated risk factors predisposing nurses to poor health outcomes and injuries.

Detailed Description

The word 'shiftwork' is commonly used to describe irregular, odd, untraditional working hours, or working hours that are away from day work period. Shiftwork dates back to the late 1800s, as applied to guardians of old kingdoms and in the military services. After the innovation of the light, shift work expanded for nonstop production as in steel factories, iron foundries, and material plants. Approximately one-fourth of the workforce in hospitals works unusual hours (away from the traditional diurnal work period) . Shiftwork has a number of advantages and disadvantages to employers, employees, and their families. The advantages for employers include optimal use of energy, facilities, and other resources through extended capital operating time. The advantages for employees include increased income, more free time for daily activities, and saving time by avoiding traffic rush hours. Shiftwork is associated with both short-term and long-term disadvantages on physical and psychophysiological health. Short-term effects include fatigue and difficulties with sleep. Difficulties with sleep are found to be the most common complaint among shift workers. Sleep disturbances were the main reasons that led shift workers to leave night shiftwork owing to disturbed health habits compared with day workers .Gastrointestinal disorders were reported 2-5 times more commonly among shift workers than daytime workers. These disorders range from minor complaints (e.g., constipation, heart burn, distension, and disturbed appetite) to serious gastrointestinal disorders, which may develop into chronic diseases such as chronic gastritis or peptic ulcers. Shiftwork has been also linked to type 2 diabetes and obesity as sleep deprivation activates the immune system and influences glucose metabolism .

An association between shiftwork and cardiovascular diseases (CVDs) has been reported. There is a higher risk for CVD such as hypertension, subclinical atherosclerosis, and ischemic heart disease compared with daytime workers . Different types of cancer have been reported in shift workers including cancers of the breast, colon, and endometrium. Shiftwork system causes circadian rhythm disruption, which is probably carcinogenic to humans.

Also, shiftwork causes disruption in both social and domestic lifestyle, which is a major consequence of shiftwork, especially with maternal employment that may have some adverse influences on their young children's cognitive and behavioral outcomes.

Conditions

Shift-work Disorder

Study Design

• Observational Model Type: CASE_CONTROL
• Study Time Perspective: RETROSPECTIVE

Study Groups

nurses in Assiut university hospitals

currently working nurses exposed to shift work

the Standard Shiftwork Index questionnaire

Intervention Type: OTHER

1. Biographical information: This includes personal data (e.g., age, sex, marital status, and domestic situations), shift details (e.g., shift start and end times), organization of shiftwork, and general job satisfaction

2. Sleep and fatigue: Measures the effect of shiftwork on perceived sleep quality and quantity and fatigue

complete blood picture

Intervention Type: OTHER

5ml blood to estimate changes of total leucocytic count, Hemoglobin, eosinophilic, monocyte

lipid profile

Intervention Type: OTHER

5ml blood to estimate changes of plasma triglycerides, total cholesterol, low-density lipoprotein cholesterol (LDL-C), and HDL-C

control group

currently working nurses not exposed to shift work

the Standard Shiftwork Index questionnaire

Intervention Type: OTHER

1. Biographical information: This includes personal data (e.g., age, sex, marital status, and domestic situations), shift details (e.g., shift start and end times), organization of shiftwork, and general job satisfaction

2. Sleep and fatigue: Measures the effect of shiftwork on perceived sleep quality and quantity and fatigue

complete blood picture

Intervention Type: OTHER

5ml blood to estimate changes of total leucocytic count, Hemoglobin, eosinophilic, monocyte

lipid profile

Intervention Type: OTHER

5ml blood to estimate changes of plasma triglycerides, total cholesterol, low-density lipoprotein cholesterol (LDL-C), and HDL-C

Interventions

the Standard Shiftwork Index questionnaire

1. Biographical information: This includes personal data (e.g., age, sex, marital status, and domestic situations), shift details (e.g., shift start and end times), organization of shiftwork, and general job satisfaction

2. Sleep and fatigue: Measures the effect of shiftwork on perceived sleep quality and quantity and fatigue

Intervention Type: OTHER

complete blood picture

5ml blood to estimate changes of total leucocytic count, Hemoglobin, eosinophilic, monocyte

Intervention Type: OTHER

lipid profile

5ml blood to estimate changes of plasma triglycerides, total cholesterol, low-density lipoprotein cholesterol (LDL-C), and HDL-C

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Active working nurses working in Assiut University Hospitals with minimum exposure to work shift for 1 year .
• Had free pre-employment records

Exclusion Criteria

• Nurses don't record shift work exposure.
• Nurses with less than 1 year exposure to shift work, or don't recorded shift work exposure.
• Nurses known to had autoimmune disorder or endocrinal disorder before joining job.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 60 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: No

Sponsors

Assiut University

OTHER

Sponsor Role: lead

Responsible Party

Mariam Roshdy Elkhayat

lecturer

Responsibility Role: PRINCIPAL_INVESTIGATOR

Central Contacts

Mariam R Elkhayat, lecturer

Role: CONTACT

mariam.elkhayat@aun.edu.eg

+20 00201003708261

Samar Mohsen, demonstrator

Role: CONTACT

samarmohsen2030@gmail.com

References

Gadallah M, Hakim SA, Mohsen A, Eldin WS. Association of rotating night shift with lipid profile among nurses in an Egyptian tertiary university hospital. East Mediterr Health J. 2017 Jun 14;23(4):295-302. doi: 10.26719/2017.23.4.295.

Reference Type: BACKGROUND

PMID: 28634980 (View on PubMed)

Merchaoui I, Bouzgarrou L, Mnasri A, Mghanem M, Akrout M, Malchaire J, Chaari N. Influence of shift work on the physical work capacity of Tunisian nurses: a cross-sectional study in two university hospitals. Pan Afr Med J. 2017 Feb 2;26:59. doi: 10.11604/pamj.2017.26.59.11279. eCollection 2017.

Reference Type: BACKGROUND

PMID: 28451036 (View on PubMed)

Ferri P, Guadi M, Marcheselli L, Balduzzi S, Magnani D, Di Lorenzo R. The impact of shift work on the psychological and physical health of nurses in a general hospital: a comparison between rotating night shifts and day shifts. Risk Manag Healthc Policy. 2016 Sep 14;9:203-211. doi: 10.2147/RMHP.S115326. eCollection 2016.

Reference Type: BACKGROUND

PMID: 27695372 (View on PubMed)

Dehring T, von Treuer K, Redley B. The impact of shift work and organisational climate on nurse health: a cross-sectional study. BMC Health Serv Res. 2018 Jul 27;18(1):586. doi: 10.1186/s12913-018-3402-5.

Reference Type: BACKGROUND

PMID: 30053871 (View on PubMed)

Other Identifiers

shift work

Identifier Type: -

Identifier Source: org_study_id