Computer-based Training of Face Recollection to Improve Face Recognition in Developmental Prosopagnosia

NCT ID: NCT04799340

Last Updated: 2022-11-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-03-12

Study Completion Date

2025-07-01

Brief Summary

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This study will examine the effectiveness of a cognitive training intervention targeting face recollection, repetition lag training, at improving face recognition in Developmental Prosopagnosia.

Detailed Description

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Conditions

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Developmental Prosopagnosia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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holistic face training + repetition lag training

Group Type EXPERIMENTAL

cognitive training

Intervention Type BEHAVIORAL

training to improve encoding and recognition of faces

waitlist control

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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cognitive training

training to improve encoding and recognition of faces

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

Developmental prosopagnosic participants will be included if they are...

* aged 18-90,
* have lifelong histories of face recognition difficulties that impact their everyday life (i.e., not associated with some event such as a stroke, seizure, etc)
* score significantly below the mean on the famous faces test and Cambridge Face Memory Test

Exclusion Criteria

Participants will be excluded from the study if they...

* have a history of a significant neurological disorder including hydrocephalus, stroke, moderate to severe traumatic brain injury (TBI), severe neuromuscular diseases, or severe hypoxia due to cardiac arrest.
* have impairments that interfere with cognitive performance, such as uncorrected hearing or vision, lack of English proficiency, musculoskeletal or other issues
* have psychiatric disorders, such as schizophrenia, major depressive disorder, bipolar disorder, chronic intractable obsessive-compulsive disorder, or agoraphobia.
* We will exclude individuals who are currently dependent on alcohol or other substances, as this may negatively impact cognitive performance.
* We will exclude participants who currently are, or within the last 6 months, participating in a behavioral or pharmacological intervention.
* Patients with a history of mild TBI or simple concussion will not be excluded as long as it was \> 6 months ago and as long as they have not had repeated concussions (\>5)
* We will include individuals with a diagnosis of ADHD as long as their medication has been consistent for the past 6 months.
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Boston VA Research Institute, Inc.

OTHER

Sponsor Role lead

Responsible Party

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Joseph DeGutis

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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VA Boston Healthcare System, 150 S. Huntington Ave.

Boston, Massachusetts, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Joseph M DeGutis, Ph.D.

Role: CONTACT

510-734-7705

Facility Contacts

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Joseph M DeGutis, Ph.D.

Role: primary

510-734-7705

Other Identifiers

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R21EY031000

Identifier Type: NIH

Identifier Source: secondary_id

View Link

R21EY031000, R01EY032510

Identifier Type: -

Identifier Source: org_study_id

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