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Rehabilitation of Facial Emotion Recognition in Alzheimer's Disease

NCT ID: NCT04730440

Last Updated: 2021-01-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

8 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-03-01

Study Completion Date

2020-03-26

Brief Summary

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This study aims to evaluate impacts of an emotion recognition rehabilitation program, named Training of Affect Recognition, on social cognition abilities in Alzheimer's disease (AD). In addition, we hypothesis that the effect of this rehabilitation will also evolve gaze strategies, behavioral disorders, and the caregiver's burden.

Detailed Description

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It is commonly admitted that social cognition impairment, like deficit in facial emotion recognition or misinterpretation of others' intentions (Theory of Mind), are associated with social behavior disorders.

This kind of disorders are observed in Fronto-Temporal Dementia, Alzheimer's Dementia (AD) and Parkinson's Disease, with severe deficits in FTD and lighter deficits in AD and PD. One explanation is that patients apply inappropriate visual exploration strategies to decode emotions and intentions of others.

Our study aims to evaluate impacts of an emotion recognition rehabilitation program, named Training of Affect Recognition, on social cognition abilities (facial emotion recognition (FER) and theory of mind (ToM)) in Alzheimer's disease (AD). In addition, we hypothesis that the effect of this rehabilitation will also evolve gaze strategies, behavioral disorders, and the caregiver's burden.

Conditions

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Alzheimer Dementia Family Caregivers

Keywords

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Video-oculography Eye-Tracking Gaze strategies Oculomotor behaviors Training of Affect Recognition Emotion recognition Facial emotion recognition Theory of Mind (ToM) Behavioral disorders Caregiver's burden Alzheimer's Dementia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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AD-TAR

AD subjects who take part to Facial Emotion Recognition rehabilitation (TAR)

AD-TAR

Intervention Type OTHER

Intervention description: 12 sessions in groups of 4 subject, over 6 weeks (2 sessions per week), using a rehabilitation program named Training of Affect Recognition (TAR).

AD-Cognitive Stimulation

AD subjects who take part to cognitive stimulation session (12 sessions during 4 weeks)

AD-Cognitive Stimulation

Intervention Type OTHER

Intervention description: 12 sessions in groups of 4 subject, over 6 weeks (2 sessions per week), using classic cognitive stimulation workshops.

Interventions

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AD-TAR

Intervention description: 12 sessions in groups of 4 subject, over 6 weeks (2 sessions per week), using a rehabilitation program named Training of Affect Recognition (TAR).

Intervention Type OTHER

AD-Cognitive Stimulation

Intervention description: 12 sessions in groups of 4 subject, over 6 weeks (2 sessions per week), using classic cognitive stimulation workshops.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* AD diagnosed according to l'IWG-2 (Dubois \& al. 2014) criteria,
* Mini-Mental State (MMS-E) ≥15
* Subject accompanied by a family caregiver and whose participation in a cognitive stimulation workshop was recommended in Memory Centre of the RAINIER Centre (Princesses Grace Hospital - Monaco)
* Written informed consent signed by patient and family caregiver.

Exclusion Criteria

* General anaesthesia within 3 months.
* Ophthalmological or neurological problems preventing a video-oculography examination.
* Oculomotor disorders such as "fixation disorders" or "ocular tracking disorders".
* Cognitive disorders of the type: visual agnosia, visuo-spatial disorder, visuo-perceptual disorder or aphasia.
* History of bipolar disorder or schizophrenia
* History of alcohol abuse.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Association de Recherche Bibliographique pour les Neurosciences

OTHER

Sponsor Role collaborator

Universite Cote d'Azur

OTHER

Sponsor Role collaborator

Centre Hospitalier Princesse Grace

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Related Links

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https://doi.org/10.1016/j.npg.2020.08.003

Remédiation de la reconnaissance des émotions faciales dans la maladie d'Alzheimer et effets sur les stratégies d'observation, les troubles du comportement et le fardeau de l'aidant

Other Identifiers

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19-02

Identifier Type: -

Identifier Source: org_study_id