Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
16 participants
INTERVENTIONAL
2022-02-25
2023-02-28
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
OTHER
QUADRUPLE
Study Groups
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NN414
To investigate the role of NN414 compared with placebo in migraine patients.
NN414
To investigate the role of NN414 on cerebral hemodynamic in migraine patients
Saline
To investigate the role of NN414 compared with placebo in migraine patients.
Saline
To investigate the role of NN414 compared with saline cerebral hemodynamic in migraine patients.
Interventions
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NN414
To investigate the role of NN414 on cerebral hemodynamic in migraine patients
Saline
To investigate the role of NN414 compared with saline cerebral hemodynamic in migraine patients.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* 18-60 years.
* 50-100 kg.
* Women of childbearing potential must use adequate contraception.
Exclusion Criteria
* Daily consumption of drugs of any kind other than oral contraceptives
* Pregnant or nursing women.
* Cardiovascular disease of any kind, including cerebrovascular diseases.
* Diabetes mellitus and other endocrinologic disease
18 Years
60 Years
ALL
No
Sponsors
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Danish Headache Center
OTHER
Responsible Party
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Lili Kokoti
MD, PhD student, Principal investigator
Locations
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Danish Headache Center
Copenhagen, Capital Region, Denmark
Countries
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Facility Contacts
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References
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Kokoti L, Al-Karagholi MA, Zhuang ZA, Amirguliyev S, Amin FM, Ashina M. Non-vascular ATP-sensitive potassium channel activation does not trigger migraine attacks: A randomized clinical trial. Cephalalgia. 2024 May;44(5):3331024241248211. doi: 10.1177/03331024241248211.
Other Identifiers
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H-20009266
Identifier Type: -
Identifier Source: org_study_id
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