Headache Inducing Effect of Cromakalim in Migraine Patients
NCT ID: NCT03228355
Last Updated: 2018-06-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
16 participants
INTERVENTIONAL
2017-05-24
2017-11-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
OTHER
QUADRUPLE
Study Groups
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Levcromakalim
Levcromakalim
To investigate the role of Levcromakalim on cerebral hemodynamic in migraine patients
Saline
Saline
To investigate the role of levcromakalim compared with saline cerebral hemodynamic in migraine patients.
Interventions
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Levcromakalim
To investigate the role of Levcromakalim on cerebral hemodynamic in migraine patients
Saline
To investigate the role of levcromakalim compared with saline cerebral hemodynamic in migraine patients.
Eligibility Criteria
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Inclusion Criteria
* 18-60 years.
* 50-90 kg.
* Women of childbearing potential must use adequate contraception.
Exclusion Criteria
* Daily consumption of drugs of any kind other than oral contraceptives
* Pregnant or nursing women.
* Cardiovascular disease of any kind, including cerebrovascular diseases.
18 Years
60 Years
ALL
No
Sponsors
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Danish Headache Center
OTHER
Responsible Party
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Mohammad Al-Mahdi Al-Karagholi
MD, PhD student
Principal Investigators
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Messoud Ashina, Professor
Role: STUDY_DIRECTOR
DHC
Locations
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Danish headache center
Copenhagen, Glostrup, Denmark
Countries
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References
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Al-Karagholi MA, Hansen JM, Guo S, Olesen J, Ashina M. Opening of ATP-sensitive potassium channels causes migraine attacks: a new target for the treatment of migraine. Brain. 2019 Sep 1;142(9):2644-2654. doi: 10.1093/brain/awz199.
Other Identifiers
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Levcromakalim
Identifier Type: -
Identifier Source: org_study_id
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