Physiological Changes With SPG Stimulation in Migraine Patients
NCT ID: NCT02510742
Last Updated: 2022-08-02
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
12 participants
INTERVENTIONAL
2015-07-31
2016-02-29
Brief Summary
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Stimulation of the SPG at low frequencies (20 Hz)is believed to cause a physiological parasympathetic upregulation which increases VMCA, concentration and cephalic vessel diameter.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
CROSSOVER
TREATMENT
DOUBLE
Study Groups
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SPG neurostimulation
SPG neurostimulation of frequency 20 Hz
Neurostimulation
Neurostimulation of sphenopalatine ganglion (SPG) of 20 Hz
Control
Sham neurostimulation of amplitude=0
Sham stimulation
Sham stimulation of sphenopalatine ganglion (SPG) with amplitude=0
Interventions
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Neurostimulation
Neurostimulation of sphenopalatine ganglion (SPG) of 20 Hz
Sham stimulation
Sham stimulation of sphenopalatine ganglion (SPG) with amplitude=0
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
ALL
No
Sponsors
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Danish Headache Center
OTHER
Responsible Party
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Song Guo
MD, PhD student
Locations
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Danish Headache Center
Copenhagen, Glostrup, Denmark
Countries
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References
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Guo S, Falkenberg K, Schytz HW, Caparso A, Jensen RH, Ashina M. Low frequency activation of the sphenopalatine ganglion does not induce migraine-like attacks in migraine patients. Cephalalgia. 2020 Aug;40(9):966-977. doi: 10.1177/0333102420921156. Epub 2020 Apr 22.
Other Identifiers
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H-1-2011-152
Identifier Type: -
Identifier Source: org_study_id
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