Vagal Nerve Stimulation and Pain Frequency, Intensity in Chronic Migraine
NCT ID: NCT06191016
Last Updated: 2024-01-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
128 participants
INTERVENTIONAL
2023-12-26
2024-10-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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nVNS Group
Experimental group will receive noninvasive vagal nerve stimulation (nVNS) in addition to prescribed medications
Vagal nerve stimulation
Experimental group will receive noninvasive vagal nerve stimulation (nVNS) in addition to prescribed medications
Sham vagal nerve stimulation
control will receive sham stimulation to vagal nerve along with prescribed medications
Sham Group
control will receive sham stimulation to vagal nerve along with prescribed medications.
Vagal nerve stimulation
Experimental group will receive noninvasive vagal nerve stimulation (nVNS) in addition to prescribed medications
Sham vagal nerve stimulation
control will receive sham stimulation to vagal nerve along with prescribed medications
Interventions
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Vagal nerve stimulation
Experimental group will receive noninvasive vagal nerve stimulation (nVNS) in addition to prescribed medications
Sham vagal nerve stimulation
control will receive sham stimulation to vagal nerve along with prescribed medications
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
18 Years
ALL
No
Sponsors
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Riphah International University
OTHER
Responsible Party
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Principal Investigators
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Mirza Obaid Baig, MSPT
Role: PRINCIPAL_INVESTIGATOR
Riphah International University
Locations
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Pakistan Railway General Hospital
Rawalpindi, Punjab Province, Pakistan
Countries
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Central Contacts
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Facility Contacts
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References
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Vukovic Cvetkovic V, Jensen RH. Neurostimulation for the treatment of chronic migraine and cluster headache. Acta Neurol Scand. 2019 Jan;139(1):4-17. doi: 10.1111/ane.13034. Epub 2018 Oct 29.
Tassorelli C, Grazzi L, de Tommaso M, Pierangeli G, Martelletti P, Rainero I, Dorlas S, Geppetti P, Ambrosini A, Sarchielli P, Liebler E, Barbanti P; PRESTO Study Group. Noninvasive vagus nerve stimulation as acute therapy for migraine: The randomized PRESTO study. Neurology. 2018 Jul 24;91(4):e364-e373. doi: 10.1212/WNL.0000000000005857. Epub 2018 Jun 15.
Lendvai IS, Maier A, Scheele D, Hurlemann R, Kinfe TM. Spotlight on cervical vagus nerve stimulation for the treatment of primary headache disorders: a review. J Pain Res. 2018 Aug 27;11:1613-1625. doi: 10.2147/JPR.S129202. eCollection 2018.
Martelletti P, Barbanti P, Grazzi L, Pierangeli G, Rainero I, Geppetti P, Ambrosini A, Sarchielli P, Tassorelli C, Liebler E, de Tommaso M; PRESTO Study Group. Correction to: Consistent effects of non-invasive vagus nerve stimulation (nVNS) for the acute treatment of migraine: additional findings from the randomized, sham-controlled, double-blind PRESTO trial. J Headache Pain. 2018 Dec 18;19(1):120. doi: 10.1186/s10194-018-0949-9.
Other Identifiers
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REC01746 Rabia Nasir
Identifier Type: -
Identifier Source: org_study_id
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