Analysis of Retinal Vessel Pulsations With Electrocardiographic Gating
NCT ID: NCT04709809
Last Updated: 2021-01-14
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
20 participants
INTERVENTIONAL
2017-07-01
2019-06-30
Brief Summary
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Detailed Description
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Based on the amplitude and on the phase shift of pulsations of retinal vessel wall, the goal is to identify a lead source of the retinal venous pulsations (IOP pulsations, or alternative sources, e.g. cerebrospinal fluid pulsations).
Subjects will be recruited from the environment of the master thesis medical students, colleagues and friends and the informed consent will be handed to them personally. Exclusion criteria will be addressed. One random eye per subject will be selected. On the study day, first the mydriasis drops - phenylephrine + tropicamide - will be applied, then ECG electrodes attached; 20 minutes after the mydriasis drops, the first set of measurements will be performed: RVA recording with ECG gating, and Pascal Dynamic Contour Tonometry (DCT) recording with ECG gating. Ten minutes after this measurements, 100% oxygen 5 liters/min through nasal cannula will be applied for 2 minutes and then the same measurements repeated. Approximate time needed for the whole run - around 60 minutes per subject, including (dis)mounting the ECG electrodes and the mydriasis time.
Conditions
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Study Design
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NA
SINGLE_GROUP
DIAGNOSTIC
NONE
Study Groups
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Experimental arm
Measurement RVA / IOP / with ECG gating
Retinal Vessel Analyzer recordings with electrocardiographic (ECG) gating
Video recordings of ocular fundus, an analysis of dynamic vessel diameters and putting them in ECG context.
Interventions
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Retinal Vessel Analyzer recordings with electrocardiographic (ECG) gating
Video recordings of ocular fundus, an analysis of dynamic vessel diameters and putting them in ECG context.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
20 Years
35 Years
ALL
Yes
Sponsors
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University Hospital, Basel, Switzerland
OTHER
Responsible Party
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Locations
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University Eye Hospital
Basel, Baseö, Switzerland
Countries
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Other Identifiers
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2017-01036
Identifier Type: -
Identifier Source: org_study_id
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