Analysis of the Variation of the Retinal Vascularization After a Prolonged Effort
NCT ID: NCT03864380
Last Updated: 2019-05-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
29 participants
OBSERVATIONAL
2019-03-15
2019-05-06
Brief Summary
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The eye allows in vivo visualization of micro-vascularisation and is considered as an excellent marker of general vascular condition.
The marathon is an intense and prolonged exercise (running 42.195 km) in aerobic environment. Thus the investigators propose to study the vascular parameters of the retina, before and after this physical exercise.
This will allow : 1) to collect information on the physiology of the retinal vascularization to prolonged effort, 2) to detect any retinal damage (haemorrhages, edema, occlusion ...), not known to date.
The results may highlight vascular effects related to retinal hypoxia (venous tortuosity, haemorrhage, venous occlusion, hypoxic edema). Furthermore the results may urge prevention in this sport more and more democratized.
the investigators hypothesized that prolonged physical exercice causes a change in retinal vascularization.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Person running a marathon
Exams performed before (1 month maximum) and after the marathon (1 hour maximum) :
Color retinography Optical Coherence Tomography - Angiography (OCT-A) Blood pressure measurement
Color retinography
Non mydriatic color retinography within 1 month before and within 1 hour after the marathon
OCT-A
Optical Coherence Tomography - Angiography within 1 month before and within 1 hour after the marathon
Blood pressure measurement
Blood pressure measurement within 1 month before and within 1 hour after the marathon
Interventions
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Color retinography
Non mydriatic color retinography within 1 month before and within 1 hour after the marathon
OCT-A
Optical Coherence Tomography - Angiography within 1 month before and within 1 hour after the marathon
Blood pressure measurement
Blood pressure measurement within 1 month before and within 1 hour after the marathon
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
18 Years
ALL
Yes
Sponsors
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Fondation Ophtalmologique Adolphe de Rothschild
NETWORK
Responsible Party
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Principal Investigators
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Martine MAUGET FAYSSE
Role: PRINCIPAL_INVESTIGATOR
Fondation A. de Rothschild
Locations
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Fondation A de Rothschild
Paris, , France
Countries
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References
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Mauget-Faysse M, Arej N, Paternoster M, Zuber K, Derrien S, Thevenin S, Alonso AS, Salviat F, Lafolie J, Vasseur V. Retinal and choroidal blood flow variations after an endurance exercise: A real-life pilot study at the Paris Marathon. J Sci Med Sport. 2021 Nov;24(11):1100-1104. doi: 10.1016/j.jsams.2021.03.013. Epub 2021 Mar 30.
Other Identifiers
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MMT_2018_10
Identifier Type: -
Identifier Source: org_study_id
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