Learning Curve of Endobronchial Intubation Using Video Laryngoscopes

NCT ID: NCT04689269

Last Updated: 2021-01-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

42 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-01-21

Study Completion Date

2021-04-30

Brief Summary

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The use of video laryngoscopes for endobronchial intubation has its own potential benefits particularly in case of airway difficulty. It is not clear how many cases are required to show competency in successful endobronchial intubation using McGrath and King Vision video laryngoscopes in simulated "easy" and "difficult" airways by novices.

The here proposed randomized crossover clinical trial will test the learning curve of using each of McGrath and King Vision video laryngoscopes in simulated "easy" and "difficult" airways with respect to the number of intubation trials for successful endobronchial intubation

Detailed Description

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Surgeries that require lung isolation have been using double-lumen tubes (DLT) for endobronchial intubation as the preferred method due to its numerous advantages.

However, the larger diameter of the DLT compared to the single-lumen tube can be more difficult to insert during intubation. \[1\] The use of video laryngoscopes (VL), which were found to have lower rates of intubation failure, reduced incidences of tracheal and laryngeal trauma, improved glottic view, and increased ease of use, are gaining interest for its use in endobronchial intubation. \[2, 3\]

The use of McGrath® VL systems for DLT endobronchial intubation has been studied and compared to that of conventional laryngoscopy, as well as that of other VL systems. When compared to the conventional Macintosh laryngoscope, McGrath® VL has been consistently associated with a better glottic visualization. \[4 - 6\] Other advantages include reduced need for external laryngeal manipulation and a lower rate of intubation-associated complications, such as bronchospasm and trauma to the oral mucosa. \[7\] However, results regarding time to intubation have been controversial.

The use of King Vision® VL for DLT endobronchial intubation has not been studied as much as the McGrath® video laryngoscope. Two studies compared the King Vision® VL system to the conventional Macintosh laryngoscope and to other VL systems. When comparing King Vision® to Macintosh laryngoscope, the time to intubation was comparable between the two devices. \[8, 9\] However, one study found that in a simulated easy airway, a significantly longer time to intubation was shown with King Vision® VL. \[9\] King Vision® VL and Macintosh laryngoscope were also comparable in terms of glottic visualization, intubation difficulty, first-pass success rates, need for optimizing maneuvers, and postoperative symptoms indicative of pharyngeal or laryngeal trauma. \[8, 9\]

Therefore, competency in endobronchial intubation using video aided laryngoscopes is built through continuous and regular hands-on training. \[10\] The learning curve of the novice is usually monitored aiming to detect when satisfactory performances are reached. This is widely done using the cumulative sum analysis (CUSUM) test, which provides an objective evaluating method of skill learning via ongoing monitoring. \[11\]

* Educational Course.

* All participants will attend a 30-minutes didactic virtual training course on the Zoom platform equipped with a slide presentation including a demonstrative video on the endobronchial intubation and the tips and tricks for using the two study devices.
* Additionally, a 5-minute hands-on practice session would be provided on each simulated airway model under close supervision by the investigators (AK, MK, SS, and TAG).
* Before each DLT intubation attempt, the manikin, laryngoscope blade, and DLT will be lubricated.
* After completing the DLT intubation, participants should have a 15-minute break before performing intubation using another laryngoscope.
* All intubations will be performed with a 35-Fr left-side DLT.
* The participants will not be allowed to watch each other to avoid any learning effect through observation.

DATA ANALYSIS

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Conditions

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Endobronchial Intubation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

A single-center, interventional, crossover, single-blind (participant), prospective, trial in simulated "easy" and "difficult" airway. The study will be conducted according to Good Clinical Practice (GCP) Guidelines and abide by the principles of the Declaration of Helsinki.
Primary Study Purpose

OTHER

Blinding Strategy

SINGLE

Participants
Participants will be blind to the data collected

Study Groups

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McGrath-King Vision

The participants will attempt double-lumen tube intubation using the McGrath (X-blade) laryngoscope then they will use the King Vision (channelled blade size 3) in the same order.

Group Type ACTIVE_COMPARATOR

The simulated "easy" airway

Intervention Type OTHER

A high-fidelity simulator (Airway Management Trainer, model AA-3100, Laerdal Medical Ltd., Orpington, England, UK) will be equipped to create an easy airway situation by adjusting the manikin until it becomes in a neutral position

The simulated "difficult" airway

Intervention Type OTHER

A high-fidelity simulator (Airway Management Trainer, model AA-3100, Laerdal Medical Ltd., Orpington, England, UK) will be equipped to create a "difficult" airway scenario will be established by placing the occiput on an Oasis Elite™ Prone Head Rest, Adult (140 mm in height) (Covidien, Mansfield, MA, USA), and inhibiting head and neck movement by securing the head with an adhesive tape, simulating the effect produced by a cervical-collar.

King Vision Laryngoscope

Intervention Type DEVICE

Using a King Vision Laryngoscope for placement of the DLT

MacGrath Laryngoscope

Intervention Type DEVICE

Using a MacGrath Laryngoscope for placement of the DLT

King Vision-McGrath

The participants will attempt double-lumen tube intubation using the King Vision (channelled blade size 3) then they will use the McGrath (X-blade) laryngoscope in the same order.

Group Type ACTIVE_COMPARATOR

The simulated "easy" airway

Intervention Type OTHER

A high-fidelity simulator (Airway Management Trainer, model AA-3100, Laerdal Medical Ltd., Orpington, England, UK) will be equipped to create an easy airway situation by adjusting the manikin until it becomes in a neutral position

The simulated "difficult" airway

Intervention Type OTHER

A high-fidelity simulator (Airway Management Trainer, model AA-3100, Laerdal Medical Ltd., Orpington, England, UK) will be equipped to create a "difficult" airway scenario will be established by placing the occiput on an Oasis Elite™ Prone Head Rest, Adult (140 mm in height) (Covidien, Mansfield, MA, USA), and inhibiting head and neck movement by securing the head with an adhesive tape, simulating the effect produced by a cervical-collar.

King Vision Laryngoscope

Intervention Type DEVICE

Using a King Vision Laryngoscope for placement of the DLT

MacGrath Laryngoscope

Intervention Type DEVICE

Using a MacGrath Laryngoscope for placement of the DLT

Interventions

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The simulated "easy" airway

A high-fidelity simulator (Airway Management Trainer, model AA-3100, Laerdal Medical Ltd., Orpington, England, UK) will be equipped to create an easy airway situation by adjusting the manikin until it becomes in a neutral position

Intervention Type OTHER

The simulated "difficult" airway

A high-fidelity simulator (Airway Management Trainer, model AA-3100, Laerdal Medical Ltd., Orpington, England, UK) will be equipped to create a "difficult" airway scenario will be established by placing the occiput on an Oasis Elite™ Prone Head Rest, Adult (140 mm in height) (Covidien, Mansfield, MA, USA), and inhibiting head and neck movement by securing the head with an adhesive tape, simulating the effect produced by a cervical-collar.

Intervention Type OTHER

King Vision Laryngoscope

Using a King Vision Laryngoscope for placement of the DLT

Intervention Type DEVICE

MacGrath Laryngoscope

Using a MacGrath Laryngoscope for placement of the DLT

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Novice medical school students in using the devices tested.
* Are not familiar with double-lumen tube (DLT) insertion.
* Having no previous experience with the two tested video laryngoscopes for tracheal intubation.

Exclusion Criteria

* Decline consent to participate.
* No written informed consent.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Imam Abdulrahman Bin Faisal University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Alaa M Khidr, MD

Role: PRINCIPAL_INVESTIGATOR

Assistant Professor & Consultant of Anesthesia and Surgical Intensive Care

Mohamed M El Tahan, MD

Role: STUDY_CHAIR

Professor of Cardiothoracic Anaesthesia & Surgical Intensive Care

Locations

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Imam Abdulrahman Bin Faisal University

Dammam, Eastern Province, Saudi Arabia

Site Status RECRUITING

Countries

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Saudi Arabia

Central Contacts

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Alaa M Khidr, MD

Role: CONTACT

+ 966 50 847 4241

Mohamed R El Tahan, MD

Role: CONTACT

+966 56 937 1849

Facility Contacts

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Alaa M Khidr, MD

Role: primary

+ 966 50 847 4241

Mohamed M El Tahan, MD

Role: backup

+966 56 937 1849

References

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Russell T, Slinger P, Roscoe A, McRae K, Van Rensburg A. A randomised controlled trial comparing the GlideScope((R)) and the Macintosh laryngoscope for double-lumen endobronchial intubation. Anaesthesia. 2013 Dec;68(12):1253-8. doi: 10.1111/anae.12322.

Reference Type BACKGROUND
PMID: 24219251 (View on PubMed)

Lewis SR, Butler AR, Parker J, Cook TM, Schofield-Robinson OJ, Smith AF. Videolaryngoscopy versus direct laryngoscopy for adult patients requiring tracheal intubation: a Cochrane Systematic Review. Br J Anaesth. 2017 Sep 1;119(3):369-383. doi: 10.1093/bja/aex228.

Reference Type BACKGROUND
PMID: 28969318 (View on PubMed)

Risse J, Schubert AK, Wiesmann T, Huelshoff A, Stay D, Zentgraf M, Kirschbaum A, Wulf H, Feldmann C, Meggiolaro KM. Videolaryngoscopy versus direct laryngoscopy for double-lumen endotracheal tube intubation in thoracic surgery - a randomised controlled clinical trial. BMC Anesthesiol. 2020 Jun 16;20(1):150. doi: 10.1186/s12871-020-01067-x.

Reference Type BACKGROUND
PMID: 32546128 (View on PubMed)

Yao WL, Wan L, Xu H, Qian W, Wang XR, Tian YK, Zhang CH. A comparison of the McGrath(R) Series 5 videolaryngoscope and Macintosh laryngoscope for double-lumen tracheal tube placement in patients with a good glottic view at direct laryngoscopy. Anaesthesia. 2015 Jul;70(7):810-7. doi: 10.1111/anae.13040. Epub 2015 Feb 27.

Reference Type BACKGROUND
PMID: 25721326 (View on PubMed)

Yoo JY, Park SY, Kim JY, Kim M, Haam SJ, Kim DH. Comparison of the McGrath videolaryngoscope and the Macintosh laryngoscope for double lumen endobronchial tube intubation in patients with manual in-line stabilization: A randomized controlled trial. Medicine (Baltimore). 2018 Mar;97(10):e0081. doi: 10.1097/MD.0000000000010081.

Reference Type BACKGROUND
PMID: 29517671 (View on PubMed)

Bakshi SG, Gawri A, Divatia JV. McGrath MAC video laryngoscope versus direct laryngoscopy for the placement of double-lumen tubes: A randomised control trial. Indian J Anaesth. 2019 Jun;63(6):456-461. doi: 10.4103/ija.IJA_48_19.

Reference Type BACKGROUND
PMID: 31263297 (View on PubMed)

El-Tahan MR, Khidr AM, Gaarour IS, Alshadwi SA, Alghamdi TM, Al'ghamdi A. A Comparison of 3 Videolaryngoscopes for Double-Lumen Tube Intubation in Humans by Users With Mixed Experience: A Randomized Controlled Study. J Cardiothorac Vasc Anesth. 2018 Feb;32(1):277-286. doi: 10.1053/j.jvca.2017.08.009. Epub 2017 Aug 4.

Reference Type BACKGROUND
PMID: 29056498 (View on PubMed)

El-Tahan MR, Al'ghamdi AA, Khidr AM, Gaarour IS. Comparison of three videolaryngoscopes for double-lumen tubes intubation in simulated easy and difficult airways: a randomized trial. Minerva Anestesiol. 2016 Oct;82(10):1050-1058. Epub 2016 May 12.

Reference Type BACKGROUND
PMID: 27171733 (View on PubMed)

Failor E, Bowdle A, Jelacic S, Togashi K. High-fidelity simulation of lung isolation with double-lumen endotracheal tubes and bronchial blockers in anesthesiology resident training. J Cardiothorac Vasc Anesth. 2014 Aug;28(4):865-9. doi: 10.1053/j.jvca.2013.07.015. Epub 2013 Nov 12.

Reference Type BACKGROUND
PMID: 24231196 (View on PubMed)

Altun D, Ozkan-Seyhan T, Camci E, Sivrikoz N, Orhan-Sungur M. Learning Curves for Two Fiberscopes in Simulated Difficult Airway Scenario With Cumulative Sum Method. Simul Healthc. 2019 Jun;14(3):163-168. doi: 10.1097/SIH.0000000000000368.

Reference Type BACKGROUND
PMID: 30908421 (View on PubMed)

Other Identifiers

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IRB-PGS-2020-01-390

Identifier Type: -

Identifier Source: org_study_id

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