Does the Use of a Videolaryngoscope Modifies Anesthetic Induction ?
NCT ID: NCT02245789
Last Updated: 2016-10-31
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
50 participants
INTERVENTIONAL
2014-09-30
2015-02-28
Brief Summary
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Tracheal intubation induces a nociceptive stimulation. Hypothesis is that the use of a videolaryngoscope induces a less pronounced nociceptive stimulation and, consequently, that it modifies the anesthetic drugs requirement. .
Detailed Description
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Patients will be randomized in two groups : intubation using a conventional MacIntosh laryngoscope or intubation using a videolaryngoscope.
If our hypothesis is confirmed, the required concentration of remifentanil, an opioid agent, will be reduced in the group using a videolaryngoscope.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Macintosh laryngoscope
Tracheal intubation will be performed using a Macintosh laryngoscope. All patients will received propofol and remifentanil anesthesia.
Tracheal intubation
Tracheal intubation will be performed using a Macintosh laryngoscope or a McGrath Mac videolaryngoscope
Propofol and remifentanil anesthesia
The standardized anesthetic procedure used a closed-loop anesthesia system with bispectral index as control variable and with two proportional-differential control algorithms, one for propofol target-controlled infusion system and one for remifentanil target-controlled infusion system.
McGrath Mac videolaryngoscope
Tracheal intubation will be performed using a McGrath Mac videolaryngoscope. All patients will received propofol and remifentanil anesthesia.
Tracheal intubation
Tracheal intubation will be performed using a Macintosh laryngoscope or a McGrath Mac videolaryngoscope
Propofol and remifentanil anesthesia
The standardized anesthetic procedure used a closed-loop anesthesia system with bispectral index as control variable and with two proportional-differential control algorithms, one for propofol target-controlled infusion system and one for remifentanil target-controlled infusion system.
Interventions
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Tracheal intubation
Tracheal intubation will be performed using a Macintosh laryngoscope or a McGrath Mac videolaryngoscope
Propofol and remifentanil anesthesia
The standardized anesthetic procedure used a closed-loop anesthesia system with bispectral index as control variable and with two proportional-differential control algorithms, one for propofol target-controlled infusion system and one for remifentanil target-controlled infusion system.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* necessity of a rapid sequence induction
* contra-indication to the use of the automated administration of propofol and of remifentanil
* contra-indication to the use of atracurium
* Otolaryngology, thoracic surgery, or intracranial surgery
18 Years
80 Years
ALL
No
Sponsors
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Hopital Foch
OTHER
Responsible Party
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Principal Investigators
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Michel Chandon, MD
Role: PRINCIPAL_INVESTIGATOR
Hopital Foch
Locations
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Institut Hospitalier Franco-Britannique
Levallois-Perret, Hauts de Seine, France
Hopital Foch
Suresnes, Hauts de Seine, France
Countries
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References
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Liu N, Chazot T, Hamada S, Landais A, Boichut N, Dussaussoy C, Trillat B, Beydon L, Samain E, Sessler DI, Fischler M. Closed-loop coadministration of propofol and remifentanil guided by bispectral index: a randomized multicenter study. Anesth Analg. 2011 Mar;112(3):546-57. doi: 10.1213/ANE.0b013e318205680b. Epub 2011 Jan 13.
Ing R, Liu N, Chazot T, Fessler J, Dreyfus JF, Fischler M, Le Guen M. Nociceptive stimulation during Macintosh direct laryngoscopy compared with McGrath Mac videolaryngoscopy: A randomized trial using indirect evaluation using an automated administration of propofol and remifentanil. Medicine (Baltimore). 2017 Sep;96(38):e8087. doi: 10.1097/MD.0000000000008087.
Other Identifiers
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2013-A01308-37
Identifier Type: OTHER
Identifier Source: secondary_id
2013/43
Identifier Type: -
Identifier Source: org_study_id