The Relationship Between Preoperative Serum Cytokine Level and Lenght of Stay in Hospital, Postoperative Pain Intensity, Functional Status, Joint Position Sense and X Ray Findings
NCT ID: NCT04487535
Last Updated: 2020-07-27
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
29 participants
INTERVENTIONAL
2018-12-01
2020-02-01
Brief Summary
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Grade 4 osteoartritis degeneration who intern the hospital for total knee arthroplasty surgery. Serum Cytokine Levels (IL-6, TNFα, IL-1β) will be assessed before surgery. Pain intensity at rest/activity and valgite angle will be evaluated before surgery, postoperative 72 hour and postoperative 6 weeks. Functional status and joint position sense will be assessed before surgery and 6 weeks after surgery. Lenght of stay in hospital (LOS) will be recorded.
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
DIAGNOSTIC
NONE
Study Groups
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Standard Total Knee Arthroplasty Surgery
Surgery performed by one orthopedic surgeon
Cytokine level
Serum cytokine level will be measured before surgery, 72nd after surgery and 6 weeks after surgery
Interventions
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Cytokine level
Serum cytokine level will be measured before surgery, 72nd after surgery and 6 weeks after surgery
Eligibility Criteria
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Inclusion Criteria
2. were scheduled for unilateral or bilateral TKA
3. were diagnosed of OA with a severity Grade 4 according to the Kellgren-Lawrence (KL) classification.
Exclusion Criteria
2. presurgery for same lower extremity
3. vascular disease
4. any chronic disease related to kidney, heart, liver
5. cancer
6. chronic inflammatory disease
45 Years
75 Years
ALL
No
Sponsors
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Karadeniz Technical University
OTHER
Hacettepe University
OTHER
Responsible Party
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Kübra Canli
Karadeniz Technical University
Locations
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Hacettepe Universty
Ankara, Sıhhıye, Turkey (Türkiye)
Countries
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Other Identifiers
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Karadeniz Technique Unıversty
Identifier Type: -
Identifier Source: org_study_id
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