The Effect of RF Genicular Nerve Block Applied in the Preoperative Period on Fast-track Total Knee Arthroplasty

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-10-19

Study Completion Date

2025-06-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

In our study, investigators plan to compare the preoperative RF and genicular nerve ablation approach in patients who underwent TKA(Total Knee Arthroplasty) using the Fast-Track protocol in terms of meeting postoperative pain, function and early discharge criteria.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Genicular Radiofrequency Ablation Versus Pulsed Radiofrequency

NCT06894147

Osteoarthritis of Knee

ACTIVE_NOT_RECRUITING NA

The Effect of Radiofrequency Ablation of Genicular Nerves on Postural Stability in Patients With Knee Osteoarthritis

NCT03816124

Osteoarthritis, Knee

UNKNOWN NA

The Effects of Ultrasound Guided Genicular Nerve Block for Knee Osteoarthritis

NCT04782401

Knee Osteoarthritis

COMPLETED NA

Evaluation of Radiofrequency Neurolysis and Chemical Neurolysis of the Genicular Nerves

NCT05340166

Knee Osteoarthritis

COMPLETED NA

The Effect of Radiofrequency Ablation on the Results of the Genicular Nerve Number in the Treatment of Knee Osteoarthritis

NCT05447624

Osteoarthritis, Knee Radiofrequency Ablation Genicular Nerve

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

One of the most important components of surgery using Fast-Track is the application of effective and well-monitored pain treatment. Post-surgical pain negatively affects the patient's early mobilization. Reduction in pain after TKA(Total Knee Arthroplasty) may not only increase short-term functional results but also increase the patient's overall satisfaction.

Genicular Nerve Radiofrequency Ablation (GNRFA) is a non-surgical treatment increasingly used in patients with advanced knee osteoarthritis. Previous studies have shown this to be an effective and safe method to reduce pain and improve functionality in this patient population.

Neurolysis of genicular nerves with radiofrequency (RF) may be useful to relieve pain and improve both function and quality of life in patients with post-TKA pain.

Investigators thought that reducing the pain of patients who underwent TKA with Fast-track in the postoperative period would contribute to early mobilization and therefore rapid functional recovery. As a result of previous studies, investigators know that genicular nerve neurolysis with RF Ablation in the preoperative period provides a reduction in postoperative pain.

Investigators routinely apply TKA applications in clinic with Fast-Track. In investigators hospital's algology outpatient clinic, genicular nerve RF ablation is routinely performed under USG or fluoroscopy guidance. In investigators study, investigators plan to compare the preoperative RF and genicular nerve ablation approach in patients who underwent TKA using the Fast-Track protocol in terms of meeting postoperative pain, function and early discharge criteria

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Knee Osteoarthritis Knee Pain Chronic

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

TKA with radiofrequency ablation genicular nerve block

Genicular nerve Radiofrequency Ablation block

Intervention Type PROCEDURE

Genicular nerve Radiofrequency Ablation block

TKA without nerve block

TKA without radiofrequency ablation genicular nerve block

No interventions assigned to this group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Genicular nerve Radiofrequency Ablation block

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Being between the ages of 40 and 85,
* Being able to understand verbal and written information given in Turkish,
* Being able to speak and understand Turkish,
* Being subjected to unilateral TKA surgery due to the diagnosis of Primary Knee osteoarthritis

Exclusion Criteria

* Patients planned for revision knee prosthesis surgery,
* Patients previously diagnosed with psychiatric disorders,
* Patients who have undergone major surgery on the extremity where TKA will be applied,
* Patients with comorbid diseases such as rheumatoid arthritis or cancer,
* Patients with a score above 3 according to the American Society of Anesthesiologists (ASA) scoring,
* Patients with neurological diseases that cause functional disability,
* Patients with flexion limitation of more than 45 degrees and extension limitation of more than 20 degrees,
* Patients who have to use hypnotic or anxiolytic drugs regularly,
* Patients with alcohol or drug addiction,
* Patients with bleeding disorders
* Patients with uncontrolled diabetes

Minimum Eligible Age

40 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No