Evaluation of Radiofrequency Neurolysis and Chemical Neurolysis of the Genicular Nerves

NCT ID: NCT05340166

Last Updated: 2023-07-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-04-24

Study Completion Date

2023-07-05

Brief Summary

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Knee osteoarthritis is one of the most common causes of pain and loss of function in the elderly population and is a source of socioeconomic costs. Selective denervation of the superior medial, superior lateral and inferior medial genicular nerves, which provide the sensory innervation of the knee joint, is an effective treatment method used to relieve pain and improve functional capacity. Radiofrequency neurolysis of genicular nerves (RFN) is accepted as an effective technique for the treatment of knee pain. However, due to higher equipment costs, longer procedure times, and procedure-related pain, alternative treatments are needed.

Detailed Description

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Conditions

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Knee Osteoarthritis

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Caregivers Investigators Outcome Assessors

Study Groups

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Radiofrequency Neurolysis

Radiofrequency Neurolysis of genicular nerves

Group Type ACTIVE_COMPARATOR

Genicular nerve radiofrequency neurolysis

Intervention Type PROCEDURE

Neurolysis of superomedial, superolateral and inferomedial genicular nerves

Chemical Neurolysis

Chemical Neurolysis of genicular nerves

Group Type EXPERIMENTAL

Genicular nerve chemical neurolysis

Intervention Type PROCEDURE

Neurolysis of superomedial, superolateral and inferomedial genicular nerves

Interventions

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Genicular nerve radiofrequency neurolysis

Neurolysis of superomedial, superolateral and inferomedial genicular nerves

Intervention Type PROCEDURE

Genicular nerve chemical neurolysis

Neurolysis of superomedial, superolateral and inferomedial genicular nerves

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

\-

Exclusion Criteria

* Coagulation disorders
* Rheumatoid disorders
* Infections
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Diskapi Teaching and Research Hospital

OTHER

Sponsor Role lead

Responsible Party

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Selin Guven Kose

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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selin guven kose

Role: PRINCIPAL_INVESTIGATOR

Diskapi Yildirim Beyazit Education and Research Hospital

Locations

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Diskapi Yildirim Beyazit Training and Research Hospital

Ankara, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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131/01

Identifier Type: -

Identifier Source: org_study_id

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