Comparison of Intra-articular Steroid Injection and Radiofrequency Thermocoagulation in Coxarthrosis Patients

NCT ID: NCT05564065

Last Updated: 2022-10-03

Basic Information

• Recruitment Status: UNKNOWN
• Clinical Phase: NA
• Total Enrollment: 40 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2021-08-01
• Study Completion Date: 2022-12-01

Brief Summary

The investigators aimed that the Comparison of effectiveness of the intra-articular steroid injection and radiofrequency thermocoagulation of the sensory branches of the femoral and obdurator nerves in coxarthrosis patients

Detailed Description

Osteoarthirtis is a deficency of articular cartilge which is caused by genetic, metabolic and biochemical factors. This is a pathologic period with cartilage, bone and sinovium destruction.

Pharmacological treatments and/or phsiycal medicine may not be enough to reduce pain in patients with chronic pain of osteoarthiritis. Intraarticular steroid injection is the most common used intervention method in analgesia of hip osteoarthirtis. Thus; cartilage inflammation can be decelerated and osteophyte formation can be prevented. On the other hand; because of less vascularity of hip joint, frequent steroid injections may cause aseptic necrosis.

In past decades, treatment to pain of hip joint pain caused by ostheoarthrits, radiofrequency ablation treatment is used to sensory nerves which cause pain. Especially, it can be a solution in patients who do not want to undergo a surgery.

Patients diagnosed with coxarthrosis will be randomly divided into two groups. One group will receive intra-articular steroid injection and the other group will receive radiofrequency thermocoagulation to the hip sensory nerve branches (femoral and obdurator). It was planned to compare the vas scores of the patients before and 1-3 months after the procedure with their effectiveness.

Conditions

Pain Hip Burning

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: SUPPORTIVE_CARE
• Blinding Strategy: NONE

Study Groups

Radiofrequency thermocoagulation of sensory branches of hip joint

There are two main nerves that carry the pain sensation of the hip joint. These nerves are the femoral and obturator nerves. The sensory branches of these nerves going to the hip joint will be detected with a radiofrequency device under fluoroscopy and percutaneous ablation will be performed.

Group Type: ACTIVE_COMPARATOR

Radiofrequency thermocoagulation of sensory branches of hip joint

Intervention Type: PROCEDURE

There are two main nerves that carry the pain sensation of the hip joint. These nerves are the femoral and obturator nerves. The sensory branches of these nerves going to the hip joint will be detected with a radiofrequency device under fluoroscopy and percutaneous ablation will be performed.

Intraarticular steroid injection of hip joint

Fluoroscopy guided percutaneous intra articular steroid injection of hip joint will be performed

Group Type: ACTIVE_COMPARATOR

Intraarticular steroid injection of hip joint

Intervention Type: PROCEDURE

Fluoroscopy guided percutaneous intra articular steroid injection of hip joint will be performed

Interventions

Radiofrequency thermocoagulation of sensory branches of hip joint

There are two main nerves that carry the pain sensation of the hip joint. These nerves are the femoral and obturator nerves. The sensory branches of these nerves going to the hip joint will be detected with a radiofrequency device under fluoroscopy and percutaneous ablation will be performed.

Intervention Type: PROCEDURE

Intraarticular steroid injection of hip joint

Fluoroscopy guided percutaneous intra articular steroid injection of hip joint will be performed

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• - Older than 18-year-old
• Clincal, radiological (Grade 3-4) and laboratory examinations ara related with diagnosis of hip joint osteoarthirtis
• Despite of previous medical and physical treatment, VAS score > 5 and above
• Norological examination without critical motor and sensory deficency
• Patients who sign informed consent.

Exclusion Criteria

• Coagulation disorders (bleeding diathesis)
• Usage of antitrombotic, anticoagulant medications
• Sepsis and local infection on intervention area
• Allergic to any of drugs which is used in intervention
• Without informed consent approval

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Istanbul University

OTHER

Sponsor Role: lead

Responsible Party

Halil Cetingok

Assistant professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Halil Cetingok, Ass. Prof

Role: STUDY_DIRECTOR

Istanbul University

Locations

Halil Cetingok

Istanbul, Fatih, Turkey (Türkiye)

Countries

Turkey (Türkiye)

Other Identifiers

2019/123

Identifier Type: -

Identifier Source: org_study_id