Effects of Concurrent Exercise Combinations in Knee Osteoarthritis:

NCT ID: NCT05054686

Last Updated: 2025-09-15

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 45 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2019-07-01
• Study Completion Date: 2021-05-30

Brief Summary

This study will include 3 different groups of intervention. First group of knee osteoarthritis patients will be applied both strengthening and 30 minutes bicycle exercises in the same session, 2 days strecthing exercises and 30 minutes walking will be given in seperate days as home program, Second group of knee osteoarthritis patients will be applied both stretching and 30 minutes bicycle exercises in the same session, strengthening exercises and 30 minutes walking will be given in seperate days as home program.Third group of knee osteoarthritis patients will be applied all stretching, strengthening and 30 minutes bicycle exercises in the same session, only 30 minutes walking will be given as home program. The primary outcome measures include the pain, function and the secondary outcome measures include the joint proprioception. The aim of this study is to investigate the effects on outcome measures increasing number of exercises in one session and to determine which exercise types are more suitable to prescribe as a home program.

Detailed Description

This study will include 3 different groups of intervention. First group of knee osteoarthritis patients will be applied both strengthening and bicycle exercises in the same session and strecthing exercises and walking will be given as home program in the days other than treatment session. Second group of knee osteoarthritis patients will be applied both stretching and bicycle exercises in the same session and strengthening exercises and walking will be given as home program in the days other than treatment session. Third group of knee osteoarthritis patients will be applied all stretching, strengthening and bicycle exercises in the same session and only walking exercise will be given as home program in the days other than treatment session. The primary outcome measures include the pain, function and the secondary outcome measures include the joint proprioception. The aim of this study is to investigate the effects increasing number of exercises in one session on outcome measures consisting of pain, function and proprioception. The pain will be evaluated both subjectively with numeric pain scale and WOMAC scale and objectively with pressure algometer. The function will be subjectively evaluated with WOMAC scale. The evaluation of joint proprioception will be evaluated with inclinometer. All the groups will be treated 2 days per week. The duration of total treatment lasts 8 weeks. All the groups practice aerobic exercises 2 days with bicycle ergometer application in the clinic, and 2 days walking outside as home program. Strecthing exercises will be applied for knee flexor and knee extensor muscles. Isometric strengthening exercises will be applied for knee extensor muscles. Isotonic strengthening exercises will be applied for hip extensor, flexor, abductor muscles and knee extensor and flexor muscles. The treatment outcomes will be evaluated at the end of 8 weeks treatment.

Conditions

Knee Osteoarthritis

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: DOUBLE

Study Groups

Combination of Stretching and Aerobic Exercises at Clinic

Combination of Stretching and Aerobic Exercises at Clinic and Strengthening and Aerobic Exercises at Home

Group Type: EXPERIMENTAL

Stretching and Aerobic Exercise at Clinic

Intervention Type: OTHER

In this group of knee osteoarthritis patients will be applied both stretching and 30 minutes bicycle exercises in the same session, strengthening exercises and 30 minutes walking will be given in seperate days as home program.

Combination of Strengthening and Aerobic Exercises at Clinic

Combination of Strengthening and Aerobic Exercises at Clinic and Stretching and Aerobic Exercises at Home

Group Type: ACTIVE_COMPARATOR

Strenghthening and Aerobic Exercise

Intervention Type: OTHER

In this group of knee osteoarthritis patients will be applied both strengthening and 30 minutes bicycle exercises in the same session, 2 days strecthing exercises and 30 minutes walking will be given in seperate days as home program.

Combination of Strengthening, Stretching and Aerobic Exercises at Clinic

Combination of Strengthening, Stretching and Aerobic Exercises at Clinic and Aerobic Exercises at Home

Group Type: ACTIVE_COMPARATOR

Strengthening, Stretching and Aerobic Exercises at clinic

Intervention Type: OTHER

In this group of knee osteoarthritis patients will be applied all stretching, strengthening and 30 minutes bicycle exercises in the same session, only 30 minutes walking will be given as home program.

Interventions

Stretching and Aerobic Exercise at Clinic

In this group of knee osteoarthritis patients will be applied both stretching and 30 minutes bicycle exercises in the same session, strengthening exercises and 30 minutes walking will be given in seperate days as home program.

Intervention Type: OTHER

Strenghthening and Aerobic Exercise

In this group of knee osteoarthritis patients will be applied both strengthening and 30 minutes bicycle exercises in the same session, 2 days strecthing exercises and 30 minutes walking will be given in seperate days as home program.

Intervention Type: OTHER

Strengthening, Stretching and Aerobic Exercises at clinic

In this group of knee osteoarthritis patients will be applied all stretching, strengthening and 30 minutes bicycle exercises in the same session, only 30 minutes walking will be given as home program.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Being diagnosed as knee osteoarthritis
• Being between the ages 45-74
• Being at stage 2-3 according to Kellegren Lawrence Classification
• Having body mass index lower than 30
• Being volunteer for participation to this study

Exclusion Criteria

• Refusing to participation to study
• Having another orthopeadic problem ralated to lower extremity
• Having uncontrollable hypertension
• Having arterial and venous disease
• Having neurological disease
• Having perceptual problem
• Having cardiac pacemaker
• Participation to physiotherapy program in the last 6 months for the same extremity
• Taking injection from the same extremity in the last 6 months

• Minimum Eligible Age: 45 Years
• Maximum Eligible Age: 73 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Istanbul University - Cerrahpasa

OTHER

Sponsor Role: lead

Responsible Party

Seda BAKTIR

Principal Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Seda BAKTIR, MSc.PT.

Role: PRINCIPAL_INVESTIGATOR

Istanbul University - Cerrahpasa

Locations

Seda Baktır

Küçükçekmece, Alkent 2000, Büyükçekmece/İstanbul, Turkey (Türkiye)

Countries

Turkey (Türkiye)

Other Identifiers

IstanbulUCSEDA

Identifier Type: -

Identifier Source: org_study_id