Comparing Exercise Programs for Managing Knee Osteoarthritis
NCT ID: NCT06711341
Last Updated: 2024-12-02
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
69 participants
INTERVENTIONAL
2023-08-01
2024-08-01
Brief Summary
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The main questions it aims to answer are:
* How do WBV, PRE, and home-based exercise compare in improving quadriceps strength in people with knee osteoarthritis?
* Which exercise modality leads to the greatest improvements in physical function, balance, knee pain, and quality of life?
Researchers will compare the three exercise regimens to determine which is most effective for improving knee function and relieving osteoarthritis symptoms.
Participants will:
* Engage in whole-body vibration exercise, progressive resistance exercise, or home-based exercise for 3 weeks.
* Undergo assessments before and at the end of the exercise program, including tests for physical function and balance (Timed Up and Go Test, 5x Sit to Stand Test) and questionnaires to evaluate knee osteoarthritis symptoms (WOMAC), quality of life (SF-36), and self-reported knee pain (Numeric Rating Scale).
Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Whole-body Vibration (WBV) Training Group
Participants undergo WBV training as outlined in the WBV intervention, 3 days per week for 3 weeks. The sessions begin with a duration of 10 minutes in the first week, with the duration increasing each week thereafter. They also perform the home exercises assigned to the Control group on the same days as their PRE sessions.
Whole-body Vibration (WBV) Training
Participants use the "Compex Winplate," designed specifically for vibration training. The device is set with a frequency of 30 Hz and an amplitude of 4 mm. Participants perform a total of 5 exercises consisting of static and dynamic squat exercises, with a 30-second rest period between sets and between different exercises. The exercises and progression over the weeks are as follows:
Week 1:
* Static squat with knees flexed at 30° - 2 sets of 30 seconds each
* Dynamic squat with knees flexed between 0-60° - 2 sets of 30 seconds each
* Fingertip-to-sole partial dynamic squat with knees flexed at 30° - 2 sets of 30 seconds each
* Consecutive weight transfer with knees flexed at 45° - 2 sets of 30 seconds each
* Single leg static squat with knees flexed at 30° - 30 seconds per leg
Subsequent Weeks: The duration of each set increases by 10 seconds each week. Each training session includes a 5-minute warm-up and a 5-minute cooldown, consisting of joint motion and muscle stretching exercises.
Progressive Resistance Exercise (PRE) Group
Participants undergo PRE training as outlined in the PRE intervention, 3 days per week for 3 weeks. The training focuses on strengthening the quadriceps muscles using ankle weights. The load is determined using the DeLorme principle at the start of each week. They also perform the home exercises assigned to the Control group on the same days as their PRE sessions.
Progressive Resistance Exercise (PRE)
Training Duration: Participants undergo approximately 15-20 minute training sessions, 3 days per week for 3 weeks.
Exercise Regimen: The training focuses on strengthening the quadriceps muscles using ankle weights. The load is determined using the DeLorme principle:
* At the beginning of each week, the 10-repetition maximum (10RM) is measured.
* During that week, participants perform their training sets as follows:
* First set: 50% of 10RM
* Second set: 75% of 10RM
* Final set: 100% of 10RM Each training session includes a 5-minute warm-up and a 5-minute cooldown, consisting of joint motion and muscle stretching exercises.
Control Group (Home-Based Exercise)
Participants perform home exercises three days per week for 3 weeks. The exercises consist of range of motion (ROM) and isometric strengthening exercises as detailed in the intervention section.
Home-Based Exercise
Protocol: Participants receive a printed document with instructions for home exercises and are instructed on how to perform the exercises.
Training Duration: Sessions are conducted three days per week for 3 weeks.
Exercise Regimen: The exercises include:
* Bilateral Quadriceps Isometric Exercise: Participants lie on their backs with a roll below each knee, pressing for 10-second holds, totaling 20 repetitions.
* Knee Extensions: Participants performed knee extensions while seated, holding each extension for 5 seconds, completing 10 repetitions per leg.
* Knee Range of Motion (ROM) Exercises: Participants lie face down and alternately bend their knees, completing 10 repetitions.
Each training session includes a 5-minute warm-up and a 5-minute cooldown, consisting of joint motion and muscle stretching exercises
Interventions
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Whole-body Vibration (WBV) Training
Participants use the "Compex Winplate," designed specifically for vibration training. The device is set with a frequency of 30 Hz and an amplitude of 4 mm. Participants perform a total of 5 exercises consisting of static and dynamic squat exercises, with a 30-second rest period between sets and between different exercises. The exercises and progression over the weeks are as follows:
Week 1:
* Static squat with knees flexed at 30° - 2 sets of 30 seconds each
* Dynamic squat with knees flexed between 0-60° - 2 sets of 30 seconds each
* Fingertip-to-sole partial dynamic squat with knees flexed at 30° - 2 sets of 30 seconds each
* Consecutive weight transfer with knees flexed at 45° - 2 sets of 30 seconds each
* Single leg static squat with knees flexed at 30° - 30 seconds per leg
Subsequent Weeks: The duration of each set increases by 10 seconds each week. Each training session includes a 5-minute warm-up and a 5-minute cooldown, consisting of joint motion and muscle stretching exercises.
Progressive Resistance Exercise (PRE)
Training Duration: Participants undergo approximately 15-20 minute training sessions, 3 days per week for 3 weeks.
Exercise Regimen: The training focuses on strengthening the quadriceps muscles using ankle weights. The load is determined using the DeLorme principle:
* At the beginning of each week, the 10-repetition maximum (10RM) is measured.
* During that week, participants perform their training sets as follows:
* First set: 50% of 10RM
* Second set: 75% of 10RM
* Final set: 100% of 10RM Each training session includes a 5-minute warm-up and a 5-minute cooldown, consisting of joint motion and muscle stretching exercises.
Home-Based Exercise
Protocol: Participants receive a printed document with instructions for home exercises and are instructed on how to perform the exercises.
Training Duration: Sessions are conducted three days per week for 3 weeks.
Exercise Regimen: The exercises include:
* Bilateral Quadriceps Isometric Exercise: Participants lie on their backs with a roll below each knee, pressing for 10-second holds, totaling 20 repetitions.
* Knee Extensions: Participants performed knee extensions while seated, holding each extension for 5 seconds, completing 10 repetitions per leg.
* Knee Range of Motion (ROM) Exercises: Participants lie face down and alternately bend their knees, completing 10 repetitions.
Each training session includes a 5-minute warm-up and a 5-minute cooldown, consisting of joint motion and muscle stretching exercises
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
2. diagnosed with knee osteoarthritis according to ACR criteria (unilateral or bilateral),
3. having grade 2 or 3 tibiofemoral knee osteoarthritis according to Kellgren-Lawrence staging,
4. having knee pain due to OA for a minimum of 3 months prior to enrollment,
5. patients whose medical treatment is not expected to change during the study period.
Exclusion Criteria
2. patients unable to walk without support,
3. having musculoskeletal limitations that prevent participation in resistance exercises (contracture, fracture, etc.),
4. other neurological, cardiac, respiratory and systemic diseases that will affect physical activity,
5. currently implementing a regular exercise or physical therapy program specific to knee OA
45 Years
70 Years
ALL
No
Sponsors
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Uludag University Hospital
UNKNOWN
Uludag University
OTHER
Responsible Party
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Mustafa Alabdallah Alalewy
Principal Investigator
Locations
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Uludağ University Hospital Physical Medicine and Rehabilitation Clinic
Bursa, Nilüfer, Turkey (Türkiye)
Countries
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Other Identifiers
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2023-15/19
Identifier Type: -
Identifier Source: org_study_id