Effects of Closed and Open Kinetic Chain Exercises

NCT ID: NCT04186143

Last Updated: 2020-06-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-11-20

Study Completion Date

2018-07-20

Brief Summary

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Osteoarthritis (OA) is a heterogeneous pathology characterized by focal cartilage degeneration and the formation of new bone around the subchondral bone and joint, which is the disruption of balance between the processes of destruction and repair in subchondral area. Knee OA is a considerable cause of disability and is present in 2-3% of all disability causes. Exercises are more noticeable than other methods because they are an easy method, low cost and long-lasting. To the best of our knowledge, the studies based on this topic are scarce. Therefore, the aim of this study was to compare the effects of open and closed kinetic chain exercises on pain, functional level, quality of life and muscle strength in patients with knee osteoarthritis.

Detailed Description

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Osteoarthritis (OA) is a heterogeneous pathology characterized by degeneration of the posterior focal cartilage and the formation of new bone around the subchondral bone and joint, which is the disruption of the balance between the processes of destruction and repair of the joint cartilage and subchondral region. Radiologically, OA was reported in the majority of people over 65 years old and in 80% of those over 75 years old. OA is the most common joint disease in the world. Knee OA is an important health problem due to pain, functional disability and reduced quality of life in patients. Studies have shown that knee OA is associated with inadequacy and pain associated with decreased quadriceps muscle strength. Strengthening education has been shown to have positive effects on OA.

Knee OA is a significant disability cause and is present in 3% of all disability causes. OA causes disability and consequent labor loss and economic loss. Therefore, OA therapy gains importance. OA therapy is classified under three headings as pharmacological methods, non-pharmacological methods and surgical methods. In non-pharmacological methods, there are a number of studies showing the effectiveness of exercise in particular. Because it is an easy method, the cost is low and it is applicable for a long time, the exercises are more important than other methods. The literature on exercise programs with optimal gains for knee osteoarthritis has not yet been established, with numerous studies reporting the importance of different types of exercise for the treatment of knee OA in the literature. Open kinetic chain exercises are frequently used to strengthen the quadriceps muscle. Closed kinetic chain exercises have been shown to increase muscle strength and improve proprioceptive function by activating more muscle spindle and joint proprioceptors. In literature, there are researches that compare closed and open kinetic chain exercises. However, these studies mostly focus on exercises after anterior cruciate ligament reconstruction. The aim of this study was to compare the effects of open and closed kinetic chain exercises on pain, functional level, quality of life and muscle strength in patients with knee osteoarthritis.

Conditions

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Osteo Arthritis Knee

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomized
Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Caregivers
Single blinded

Study Groups

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Experimental-Study Group

In addition to the conservative treatment of the control group, closed cinetic chain exercises were applied for 12 weeks.

Group Type EXPERIMENTAL

Closed Cinetic Chain Exercises

Intervention Type OTHER

Sit to stand, mini squat, anterior lunge, step up exercises are performed as Closed Cinetic Chain Exercises.

Active Comparator

In addition to the conservative treatment of the control group, opened cinetic chain exercises were applied for 12 weeks.

Group Type ACTIVE_COMPARATOR

Open Kinetic Chain Exercises

Intervention Type OTHER

Isometric quadriceps, isotonic quadriceps, hip extension and hip adduction exercises are performed as Open Kinetic Chain Exercises.

Control Group

Conservative treatment was applied for 12 weeks.

Group Type OTHER

Control Group

Intervention Type OTHER

Control Group was followed up by conservative treatment and home program for 12 weeks and they were asked to apply the home program three days in a week. Exercise brochure was handed out for home program. Quadriceps strength and harmstring stretch exercises were applied.

Interventions

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Closed Cinetic Chain Exercises

Sit to stand, mini squat, anterior lunge, step up exercises are performed as Closed Cinetic Chain Exercises.

Intervention Type OTHER

Open Kinetic Chain Exercises

Isometric quadriceps, isotonic quadriceps, hip extension and hip adduction exercises are performed as Open Kinetic Chain Exercises.

Intervention Type OTHER

Control Group

Control Group was followed up by conservative treatment and home program for 12 weeks and they were asked to apply the home program three days in a week. Exercise brochure was handed out for home program. Quadriceps strength and harmstring stretch exercises were applied.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* the presence of knee osteoarthritis Grade 2 and Grade 3 based on Kellgren Lawrence Classification,
* volunteering to participate in the study.

Exclusion Criteria

* the presence of active synovitis,
* participation physiotherapy program in the last 6 months,
* systemic and cardiovascular diseases,
* neurological and orthopedic problems affecting walking and standing,
* lower extremity surgery
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hacettepe University

OTHER

Sponsor Role lead

Responsible Party

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Caner Karartı

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Caner KARARTI

Kırşehir, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Heywood S, McClelland J, Geigle P, Rahmann A, Villalta E, Mentiplay B, Clark R. Force during functional exercises on land and in water in older adults with and without knee osteoarthritis: Implications for rehabilitation. Knee. 2019 Jan;26(1):61-72. doi: 10.1016/j.knee.2018.11.003. Epub 2019 Jan 2.

Reference Type RESULT
PMID: 30611642 (View on PubMed)

Olagbegi OM, Adegoke BO, Odole AC. Effectiveness of three modes of kinetic-chain exercises on quadriceps muscle strength and thigh girth among individuals with knee osteoarthritis. Arch Physiother. 2017 Jul 19;7:9. doi: 10.1186/s40945-017-0036-6. eCollection 2017.

Reference Type RESULT
PMID: 29340203 (View on PubMed)

Resende RA, Kirkwood RN, Deluzio KJ, Morton AM, Fonseca ST. Mild leg length discrepancy affects lower limbs, pelvis and trunk biomechanics of individuals with knee osteoarthritis during gait. Clin Biomech (Bristol). 2016 Oct;38:1-7. doi: 10.1016/j.clinbiomech.2016.08.001. Epub 2016 Aug 3.

Reference Type RESULT
PMID: 27509479 (View on PubMed)

Other Identifiers

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2019900

Identifier Type: -

Identifier Source: org_study_id

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