Central Sensitization in Knee Osteoarthritis

NCT ID: NCT04308967

Last Updated: 2022-10-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-03-20

Study Completion Date

2021-04-30

Brief Summary

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The stimuli that activate nociceptors cause the dorsal horn of the spinal cord neurons to be sensitive to low-intensive afferent stimuli by decreasing the excitation threshold in patients with osteoarthritis. Although painful stimuli disappear, this situation causes pain to continue and a decrease in quality of life. Therefore, central sensitization should be considered and treated in patients with osteoarthritis. Although various pharmacological and electrophysiological agents are used in the treatment of central sensitization, adequate efficacy is not provided in patients with osteoarthritis. The aim of this study is to investigate the effects of balance exercises on central sensitization in patients with knee osteoarthritis.

Detailed Description

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Conditions

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Osteo Arthritis Knee Central Sensitisation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Balance exercises and information

Balance exercises six weeks and three days in a week and information about central sensitisation.

Group Type EXPERIMENTAL

balance exercises

Intervention Type OTHER

Three-stage progressive balance exercises will be applied.

Information

Information about central sensitisation.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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balance exercises

Three-stage progressive balance exercises will be applied.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Being diagnosed with primary knee osteoarthritis according to American College of Rheumatology criteria,
* To be stage 2-3-4 knee osteoarthritis according to Kellgren Lawrence radiological staging,
* To be with a central sensitization score of over 40 according to the CSI,
* To be able to fill the scales and accept to participate in the study.

Exclusion Criteria

* Being diagnosed with secondary osteoarthritis or inflammatory rheumatic disease,
* Having cognitive impairment,
* To have been treated with physiotherapy, with an intra articular injection or with a surgery from the knee within a maximum of six months
* Having various diseases that may adversely affect performing balance exercises,
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cukurova University

OTHER

Sponsor Role lead

Responsible Party

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Emre Tirasci

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Cukurova University, Faculty of Medicine, Physical Medicine and Rehabilitation Clinic

Adana, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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96/17

Identifier Type: -

Identifier Source: org_study_id

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