Evaluation of the Effect of Central Sensitivity on Pain and Functional Status After Total Knee Joint Replacement Surgery
NCT ID: NCT06553118
Last Updated: 2024-08-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
80 participants
OBSERVATIONAL
2024-08-12
2026-02-12
Brief Summary
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The aim of this study is to evaluate whether there is a difference in preoperative and postoperative pain and functional status between patients with and without central sensitization with knee osteoarthritis.
When the literature was reviewed, it was seen that central sensitization was one of the important mechanisms that caused pain in knee osteoarthritis, and it was determined that this had negative consequences in terms of postoperative pain and improvement in functional status. In this study, the effect of central sensitization on the results will be investigated by evaluating pain and functional status before and after knee total joint prosthesis in two groups of knee osteoarthritis patients, with and without central sensitization, and by comparing the groups.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Central Sensitization Group
Patients with central sensitization
Total knee arthroplasty
Patients already admitted for total knee arthroplasty for knee osteoarthritis will have the procedure as planned
Non-sensitized Group
Patients without central sensitization
Total knee arthroplasty
Patients already admitted for total knee arthroplasty for knee osteoarthritis will have the procedure as planned
Interventions
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Total knee arthroplasty
Patients already admitted for total knee arthroplasty for knee osteoarthritis will have the procedure as planned
Eligibility Criteria
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Inclusion Criteria
* Planning for total joint replacement surgery for the knee
* Being between the ages of 60-75
Exclusion Criteria
* Planning for knee total joint prosthesis revision
* Having uncontrolled systemic disease (such as diabetes mellitus, hypertension, thyroid disease)
* Having neuromuscular disease
* Having a body mass index over 40
60 Years
75 Years
ALL
No
Sponsors
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Istanbul University
OTHER
Responsible Party
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Fatma Merih Akpınar
Assistant Professor
Principal Investigators
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Fatma Merih Akpınar
Role: PRINCIPAL_INVESTIGATOR
Istanbul Faculty of Medicine
Central Contacts
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Other Identifiers
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2024/1010
Identifier Type: -
Identifier Source: org_study_id
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