Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
45 participants
OBSERVATIONAL
2018-01-10
2019-03-10
Brief Summary
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Methods: The study consisted of three groups as group 1; healthy controls (C, n=15), group 2; periodontitis patients with stage 3 grade B (P, n=15), and group 3; peri-implantitis patients (PI, n=15). Periodontal clinical parameters as the plaque index (PI), gingival index (GI) and clinical attachment levels (CAL) were recorded. Gingival biopsies were obtained from all participants and biopsy samples underwent histological tissue processing. Hematoxylin-eosin (H\&E) and immunohistochemistry staining were performed. Total inflammatory cell counts and fibroblast cell density were evaluated on H\&E-stained slides while PPAR-γ, RXR-α, and VDR were evaluated via immunohistochemistry.
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
CROSS_SECTIONAL
Study Groups
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group 1;
healthy controls (C, n=15),
Gingival biopsies
Gingival biopsies were obtained from all participants and biopsy samples underwent histological tissue processing.
group 2
periodontitis patients with stage 3 grade B; (P, n=15)
Gingival biopsies
Gingival biopsies were obtained from all participants and biopsy samples underwent histological tissue processing.
group 3
peri-implantitis patients (PI, n=15).
Gingival biopsies
Gingival biopsies were obtained from all participants and biopsy samples underwent histological tissue processing.
Interventions
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Gingival biopsies
Gingival biopsies were obtained from all participants and biopsy samples underwent histological tissue processing.
Eligibility Criteria
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Inclusion Criteria
* periodontitis patients
* periimplantitis patients
Exclusion Criteria
* systemically compromised patients
ALL
Yes
Sponsors
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Tokat Gaziosmanpasa University
OTHER
Responsible Party
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mehmet murat taskan
Assistant Professor
Locations
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Gaziosmanpasa University
Tokat Province, , Turkey (Türkiye)
Countries
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Other Identifiers
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Gaziosmanpasa University
Identifier Type: -
Identifier Source: org_study_id
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