Observing the Changes of Endocrine and Metabolism in Patients With Thalassemia Major

NCT ID: NCT03951818

Last Updated: 2021-02-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-04-01

Study Completion Date

2024-04-01

Brief Summary

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Patient with thalassemia major have many endocrine diseases, such as hypopituitarism, hypothyroidism, hypoparathyroidis, osteoporosis, and etc.. These problems may be due to anemia itself or related to iron deposition. This study aimed to investigate the endocrine aspect of thalassemia major patients in Taiwan in order to introduce early intervention or treatment in the future.

Detailed Description

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Conditions

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Thalassemia Major

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Clinical diagnosis of Thalassemia major
* Patients of 20-85 years old

Exclusion Criteria

* Patients younger than 20 years old.
* Patients older than 85 years old.
* Patients who are pregnant
Minimum Eligible Age

20 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Taiwan University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Shyang-Rong Shih, MD, PhD

Role: STUDY_DIRECTOR

National Taiwan University Hospital

Locations

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Shyang-Rong Shih

Taipei, , Taiwan

Site Status RECRUITING

Countries

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Taiwan

Central Contacts

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Shyang-Rong Shih, MD, PhD

Role: CONTACT

+886-972653337

Facility Contacts

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Shyang-Rong Shih

Role: primary

886-23123456

References

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Yang WP, Chang HH, Li HY, Lai YC, Huang TY, Tsai KS, Lin KH, Lin DT, Jou ST, Lu MY, Yang YL, Chou SW, Shih SR. Iron Overload Associated Endocrine Dysfunction Leading to Lower Bone Mineral Density in Thalassemia Major. J Clin Endocrinol Metab. 2020 Apr 1;105(4):dgz309. doi: 10.1210/clinem/dgz309.

Reference Type DERIVED
PMID: 31907538 (View on PubMed)

Other Identifiers

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201903041RINB

Identifier Type: -

Identifier Source: org_study_id

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