Clinical and Surgical Outcomes of Thyroid Carcinoma in Children and Adolescents
NCT ID: NCT06592118
Last Updated: 2024-09-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
3068 participants
OBSERVATIONAL
2000-01-01
2024-08-31
Brief Summary
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Detailed Description
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Key areas of investigation include the examination of clinical characteristics such as tumor size, location, and stage at diagnosis, as well as treatment approaches including surgery types and their impact on patient outcomes. Additionally, the study will assess the causes of death and overall survival rates among these young patients, aiming to identify any significant prognostic factors.
By leveraging the robust and extensive data available in the SEER database, this study seeks to uncover critical insights into the management of follicular and \[specific type\] carcinoma in pediatric and adolescent populations. The findings are expected to contribute to the development of more tailored and effective therapeutic strategies, ultimately improving long-term survival and quality of life for affected patients.
Conditions
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Study Design
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COHORT
RETROSPECTIVE
Study Groups
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FTC
Pediatric and Adolescent Patients with Follicular Thyroid Carcinoma
Different Pathological Types (FTC vs PTC)
Comprehensive Comparison of Pediatric and Adolescent Follicular Thyroid Carcinoma and Papillary Thyroid Carcinoma Patients
PTC
Pediatric and Adolescent Patients with Papillary Thyroid Carcinoma
Different Pathological Types (FTC vs PTC)
Comprehensive Comparison of Pediatric and Adolescent Follicular Thyroid Carcinoma and Papillary Thyroid Carcinoma Patients
Interventions
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Different Pathological Types (FTC vs PTC)
Comprehensive Comparison of Pediatric and Adolescent Follicular Thyroid Carcinoma and Papillary Thyroid Carcinoma Patients
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Age range: Pediatric and adolescent patients (ages 1-18 years).
Exclusion Criteria
1 Year
18 Years
ALL
No
Sponsors
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Dezhou Hospital Qilu Hospital of Shandong University
OTHER
Responsible Party
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Principal Investigators
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Tao Zhang, MD
Role: STUDY_DIRECTOR
Qilu Hospital of Shandong University Dezhou
References
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Cistaro A, Quartuccio N, Garganese MC, Villani MF, Altini C, Pizzoferro M, Piccardo A, Cabria M, Massollo M, Maghnie M, Campenni A, Siracusa M, Baldari S, Panareo S, Urso L, Bartolomei M, De Palma D, Grossi A, Mazzoletti A, Dondi F, Bertagna F, Giubbini R, Albano D. Prognostic factors in children and adolescents with differentiated thyroid carcinoma treated with total thyroidectomy and RAI: a real-life multicentric study. Eur J Nucl Med Mol Imaging. 2022 Mar;49(4):1374-1385. doi: 10.1007/s00259-021-05586-8. Epub 2021 Oct 19.
de Souza Reis R, Gatta G, de Camargo B. Thyroid carcinoma in children, adolescents, and young adults in Brazil: A report from 11 population-based cancer registries. PLoS One. 2020 May 1;15(5):e0232416. doi: 10.1371/journal.pone.0232416. eCollection 2020.
Moleti M, Aversa T, Crisafulli S, Trifiro G, Corica D, Pepe G, Cannavo L, Di Mauro M, Paola G, Fontana A, Calapai F, Cannavo S, Wasniewska M. Global incidence and prevalence of differentiated thyroid cancer in childhood: systematic review and meta-analysis. Front Endocrinol (Lausanne). 2023 Sep 19;14:1270518. doi: 10.3389/fendo.2023.1270518. eCollection 2023.
Liu Y, Meng T, Ma S, Zheng Y, Miao Y, Zhang T. Clinical characteristics, surgical approaches, and prognosis of follicular and papillary thyroid cancer in children and adolescents: a retrospective cohort study. Pediatr Surg Int. 2025 Feb 28;41(1):89. doi: 10.1007/s00383-025-05990-3.
Other Identifiers
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DZSRMYYZC2024095
Identifier Type: -
Identifier Source: org_study_id
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