The Effect of Vinegar Consumption on Visceral Fat and Blood Glucose Concentration

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

102 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-01-05

Study Completion Date

2018-08-15

Brief Summary

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The purpose of this study is to test the potential ability of vinegar to significantly decrease visceral fat in healthy adults with "central obesity". During the 8-week trial, participants will either consume a low-dose vinegar pill (control treatment) or a vinegar drink twice per day.

Research Aim and Hypothesis H1 Daily vinegar consumption will be associated with loss in visceral fat (as measured by DXA) after 8 weeks compared to the placebo treatment (low-vinegar pill) in a group of healthy adults with "central obesity".

H2 Daily vinegar consumption will be associated with a decrease in abdominal circumference after 8 weeks compared to the placebo treatment (low-vinegar pill) in a group of healthy adults with "central obesity".

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Detailed Description

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This randomized, placebo-controlled experimental trial will last 8 weeks. At the initial visit (consenting visit lasting about 20 minutes) the participant will sign the consent and complete a short health questionnaire and a short questionnaire on tooth erosion. Body height and weight and waist circumference will also be measured. Qualifying participants will be stratified by gender, age, weight, and waist circumference, then randomized into two groups: the intervention group, vinegar drinks (VIN) or the control group, vinegar pills (CON). The participants will know which treatment they are given but they will not know which group (control vs. placebo) they are in. Those who receive the VIN will be instructed to drink 2 tablespoons of red wine vinegar (provided) mixed with water twice each day for weeks 1 to 8 of the trial. Those in the CON group will be instructed to take one vinegar pill (provided) each day for weeks 1-8 of the trial. Participants will be instructed to maintain their current diet and exercise habits during the study.

Conditions

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Visceral Obesity Tooth Erosion Insulin Resistance

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Qualifying participants will be stratified by gender, age, weight, and waist circumference, then randomized into two groups: the intervention group, vinegar drinks (VIN) or the control group, vinegar pills (CON).

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Investigators

All participants will receive 'vinegar' either in liquid form (active) or pill (not active as acetic acid concentration is below threshold of effect). Investigators measuring outcome variables (visceral fat, tooth enamel, and blood indices) are blinded to treatment assignment.

Study Groups

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Liquid vinegar

Participants in this arm were instructed to drink 2 tablespoons of red wine vinegar (provided) mixed with water twice each day for weeks 1 to 8 of the trial.

Group Type EXPERIMENTAL

liquid vinegar

Intervention Type DIETARY_SUPPLEMENT

6% red wine vinegar (2 tablespoons providing 1.7 g acetic acid)

Vinegar pill

Participants in the control group were instructed to take one vinegar pill (provided) each day for weeks 1-8 of the trial.

Group Type PLACEBO_COMPARATOR

vinegar pill

Intervention Type DIETARY_SUPPLEMENT

Apple Cider Vinegar Tablets (1 tablet providing 0.0225 g acetic acid)

Interventions

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liquid vinegar

6% red wine vinegar (2 tablespoons providing 1.7 g acetic acid)

Intervention Type DIETARY_SUPPLEMENT

vinegar pill

Apple Cider Vinegar Tablets (1 tablet providing 0.0225 g acetic acid)

Intervention Type DIETARY_SUPPLEMENT

Other Intervention Names

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VIN CON

Eligibility Criteria

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Inclusion Criteria

* Nonsmoking
* Not pregnant or lactating if female
* No active disease state or medication use affecting blood glucose or cholesterol (additionally, individuals on digoxin or diuretics will be excluded but other medications in use \>3 months will be allowed)
* No food restrictions or special diet
* BMI range: 22-35
* Waist circumference \>34 (women) and \>39 (males)
* Sedentary (exercising \< 3 days/week)

Exclusion Criteria

* Unwilling to take a vinegar supplement daily for 8 week or follow other aspects of study protocol
* Recent abdominal surgery or condition causing abdominal discomfort/distention (such as acid reflux, ascites, pancreatitis, diverticulitis/diverticulosis, Crohn's disease, and/or irritable bowel syndrome)

Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes