Brain Oxygenation During Cardiopulmonary Resuscitation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-02-24

Study Completion Date

2019-04-30

Brief Summary

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The study is aimed to assess (a) the incidence of hyperoxia at the point of return of spontaneous circulation (ROSC) and (b) the role of arterial blood oxygen partial pressure to brain oxygenation during out-of-hospital cardiac arrest. 80 adult patients will be recruited in a physician staffed helicopter emergency medical services. Brain regional oxygen saturation and invasive blood pressure are monitored until hospital admission and arterial blood gases are analyzed immediately when the unit arrives to the patient and again at the time of ROSC.

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Detailed Description

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Conditions

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Cardiac Arrest, Out-Of-Hospital

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Standard cardiopulmonary resuscitation

Standard Advanced Life Support based on guidelines 2015, including mechanical chest compression device

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* out-of-hospital cardiac arrest of presumed cardiac origin
* resuscitation will be continued at least 5 minutes (if return of spontaneous circulation not achieved earlier) after arrival of physician team

Exclusion Criteria

* do-not-attempt-resuscitation (DNAR) order or withdrawal of treatment by prehospital critical care physician
* return of spontaneous circulation achieved before physician-led critical team arrives
* external cause for cardiac arrest (e.g. trauma, suffocation)
* workload too high or environment too dangerous to perform study procedures

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No