A Pilot Study of Hand Function in Children With Cerebral Palsy Undergoing Intensive Neurophysiological Rehabilitation

NCT ID: NCT03454412

Last Updated: 2021-05-25

Study Results

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

44 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-03-19

Study Completion Date

2019-05-01

Brief Summary

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The aim of the study is to observe the effects of Intensive Neurophysiological Rehabilitation System on hand function in children with spastic cerebral palsy.

Detailed Description

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Intensive Neurophysiological Rehabilitation System is a novel multimodal rehabilitation approach that combines different treatment modalities. The treatment course lasts for 2 weeks with daily therapy up to 4 hours. Main treatment programs include biomechanical correction of the spine, extremity joint mobilization, physical and occupational therapy, reflexotherapy, special massage system, rhythmical group exercises, mechanotherapy and computer games therapy and some other.

Preliminary observational studies indicate an improvement of gross and fine motor functions in children with Cerebral Palsy after the treatment course.

The aim of the study is to observe the effects of Intensive Neurophysiological Rehabilitation System on hand function in children with spastic cerebral palsy.

About 50 patients with spastic forms of cerebral palsy with mild to moderate impairment of hand function (Level I to III according to Manual Abilities Classification System) would be evaluated before and after the two-week treatment course.

This study may help to generate the hypothesis of the effects of the Intensive treatment course on hand function abilities and to prepare a future randomized controlled trial.

Conditions

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Cerebral Palsy

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Interventions

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Intensive Neurophysiological Rehabilitation

Intensive Neurophysiological Rehabilitation System (INRS) is a combination of different treatment modalities that complement and reinforce each other. It includes spinal manipulative therapy, physical therapy, occupational therapy, joints mobilization techniques, special massage therapy, mechanotherapy, computer games therapy and other treatments with daily duration up to 4 hours.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Spastic cerebral palsy: uni- and bilateral
* Age: 6-15
* Level I-III according to Manual Ability Classification System (MACS)

Exclusion Criteria

* Ataxic or dyskinetic cerebral palsy
* Non-cooperative behavior
* Moderate to severe mental deficit
* Severe contractures of upper extremity joints
* Upper extremities trauma within 6 months prior to the study
* Previous hand surgery
* Epilepsy with frequent seizures
Minimum Eligible Age

6 Years

Maximum Eligible Age

15 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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International Clinic of Rehabilitation, Ukraine

OTHER

Sponsor Role lead

Responsible Party

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Oleh Kachmar

Head of Innovative Technologies Department

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Oleh Kachmar, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

International Clinic of Rehabilitation, Ukraine

Locations

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International Clinic of Rehabilitation

Truskavets, Lviv Oblast, Ukraine

Site Status

Countries

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Ukraine

References

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Kachmar O, Voloshyn T, Hordiyevych M. Changes in Muscle Spasticity in Patients With Cerebral Palsy After Spinal Manipulation: Case Series. J Chiropr Med. 2016 Dec;15(4):299-304. doi: 10.1016/j.jcm.2016.07.003. Epub 2016 Sep 28.

Reference Type BACKGROUND
PMID: 27857638 (View on PubMed)

Koziavkin VI, Voloshin TB, Gordievich MS, Kachmar OA. [Changes of motor function in patients with cerebral palsy during the treatment using the intensive neurophysiological rehabilitation system]. Zh Nevrol Psikhiatr Im S S Korsakova. 2012;112(7 Pt 2):14-7. Russian.

Reference Type BACKGROUND
PMID: 23330186 (View on PubMed)

Kozyavkin VI, Kachmar OO. Rehabilitation outcome assessment methods in Intensive neurophysiological rehabilitation system. Ukrayinskyj Medychnyj Chasopys. 2003;3(35):61-66. [in Ukrainian]

Reference Type BACKGROUND

Kozyavkin VI, Babadagly MO, Lun GP. : . Intensive Neurophysiological Rehabilitation System-the Kozyavkin Method. A Manual for Rehabilitation Specialists, Design studio Papuga; Lviv, Ukraine, 2012

Reference Type BACKGROUND

Provided Documents

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Document Type: Study Protocol, Statistical Analysis Plan, and Informed Consent Form

View Document

Other Identifiers

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N-02-2018

Identifier Type: -

Identifier Source: org_study_id

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