Comparison of High-flow Oxygen vs. BiPAP in Type II (Hypercapnic) Respiratory Failure
NCT ID: NCT03443479
Last Updated: 2020-07-28
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
324 participants
OBSERVATIONAL
2015-04-01
2019-07-01
Brief Summary
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Detailed Description
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All patients treated with HFNC were treated with an Optiflow device (Fisher\&Paykel). Various Bilevel positive airway pressure (BiPAP) devices were used during the study period.
All ventilatory parameters were set according to the treating physicians' preferences.
Conditions
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Study Design
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COHORT
RETROSPECTIVE
Study Groups
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Patients with type II ARF
All patients with type II respiratory failure that were deemed by the treating physician to require ventilatory support either with non-invasive ventilation (NIV) or High-Flow Nasal Cannula (HFNC).
Non-Invasive Ventilation
Treatment with Non-Invasive Ventilation by BiPAP. Different BiPAP models are in use. Ventilation parameters set at the discretion of the treating physician.
High-Flow Nasal Cannula
Treatment with a High-Flow Nasal Cannula. The Optiflow device by Fisher\&Paykel used in all cases. Flow and fraction of inspired oxygen (FiO2) parameters at the discretion of the treating physician.
Interventions
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Non-Invasive Ventilation
Treatment with Non-Invasive Ventilation by BiPAP. Different BiPAP models are in use. Ventilation parameters set at the discretion of the treating physician.
High-Flow Nasal Cannula
Treatment with a High-Flow Nasal Cannula. The Optiflow device by Fisher\&Paykel used in all cases. Flow and fraction of inspired oxygen (FiO2) parameters at the discretion of the treating physician.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Blood venous gas showing partial pressure of carbon dioxide\>50 mmHg before beginning therapy with either NIV or HFNC
Exclusion Criteria
* End-of-life care
* Lack of gas before the beginning of NIV or HFNC
18 Years
ALL
No
Sponsors
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Hôpital de Verdun
OTHER
Responsible Party
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Principal Investigators
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Ivan Pavlov, MD
Role: PRINCIPAL_INVESTIGATOR
Ivan Pavlov MD CP inc
Locations
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Hôpital de Verdun
Montreal, Quebec, Canada
Countries
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Other Identifiers
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OF1
Identifier Type: -
Identifier Source: org_study_id
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