Association of Plasma Transfusions and Invasive Fungal Infection

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-01-01

Study Completion Date

2023-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Although lacking strong evidences, plasma transfusions are commonly used in critically ill neonates. To date, the relationships between plasma transfusions and nosocomial infection remain controversial and no study has reported the relationships between plasma transfusion and invasive fungal infection (IFI)

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

The Th17/Treg Cells and IL-23/IL-17 Axis and Early Enteral Nutrition in Sepsis

NCT03385850

Sepsis Immune System Disorder Enteral Feeding

COMPLETED NA

A Multi-Center Data System and Collaborative Network in China for Severe Infection and Sepsis Children

NCT04955210

Critical Illness Severe Sepsis

RECRUITING

Sepsis-associated Thrombocytopenia and Platelet Transfusion （STAPT）

NCT07230067

Sepsis Sepsis and Coagulopathy

RECRUITING

Procalcitonin and Endotoxin Sequential Levels to Optimize the Treatment of Bloodstream Infections

NCT00870623

Bloodstream Infection

COMPLETED

Treatment Outcome With Antibiotic Use and Its Resistance Pattern Among Patient With Neonatal Sepsis

NCT05742477

Neonatal Sepsis

UNKNOWN

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Our aim is to explore the association between plasma transfusions and IFI in critically ill neonates

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Plasma Administration Invasive Fungal Infection Neonatal Infection

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

plasma transfusions

The critical ill neonates with plasma transfusions

plasma transfusions

Intervention Type DRUG

These critical ill neonates with plasma transfusions

non-plasma transfusions

The critical ill neonates without plasma transfusions

non-plasma transfusions

Intervention Type DRUG

These critical ill neonates without plasma transfusions

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

plasma transfusions

These critical ill neonates with plasma transfusions

Intervention Type DRUG

non-plasma transfusions

These critical ill neonates without plasma transfusions

Intervention Type DRUG

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* all critically ill neonates admitted in hospital

Exclusion Criteria

* severe congenital abnormality;
* died within 24 hours or left neonatal intensive care unit within 24 hours according to their parents' decisions;
* parents' decision not to participate.

Minimum Eligible Age

0 Hours

Maximum Eligible Age

24 Hours

Eligible Sex

ALL

Accepts Healthy Volunteers

No