Orange Juice Consumption and Glucose Metabolism and Antioxidative Status

NCT ID: NCT02974478

Last Updated: 2017-04-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

26 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-04-30

Study Completion Date

2016-12-31

Brief Summary

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Aim of the study is to investigate the impact of orange juice consumption (with meals or between meals) as well as sugar sweetened beverage (SSB) consumption (between meals) on glucose homeostasis and antioxidative status.

Detailed Description

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Duration of the study is 3x three weeks including one wash-out week each followed by two weeks of juice/SSB consumption under free living conditions.

During wash-out weeks consumption of orange juice or citrus fruits is restricted.

During intervention weeks, participants are asked to eat three regular meals per day without snacking. Intervention weeks are (i) orange juice consumption with meals (ii) orange juice consumption between meals and (iii) SSB consumption between meals. Daily energy intake with orange juice/SSB is 20% of individual energy requirement. Additional caloric beverages (SSB, juice, coffee with sugar/milk, alcohol) are not allowed. At the beginning and the end of each intervention phase insulin sensitivity and antioxidative status are assessed.

Conditions

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Healthy

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Orange juice with meals

Effect of orange juice consumption with three meals per day (without snacking) on glucose metabolism and antioxidative status

Group Type EXPERIMENTAL

Orange juice with meals

Intervention Type DIETARY_SUPPLEMENT

orange juice (20% of energy requirement/day)

Orange juice between meals

Effect of orange juice consumption between three meals per day (without snacking) on glucose metabolism and antioxidative status

Group Type EXPERIMENTAL

Orange juice between meals

Intervention Type DIETARY_SUPPLEMENT

orange juice (20% of energy requirement/day)

Sugar sweetened beverage between meals

Effect of sugar sweetened beverage consumption between three meals per day (without snacking) on glucose metabolism and antioxidative status

Group Type EXPERIMENTAL

Sugar sweetened beverage between meals

Intervention Type DIETARY_SUPPLEMENT

Sugar sweetened beverage (20% of energy requirement/day)

Interventions

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Orange juice with meals

orange juice (20% of energy requirement/day)

Intervention Type DIETARY_SUPPLEMENT

Orange juice between meals

orange juice (20% of energy requirement/day)

Intervention Type DIETARY_SUPPLEMENT

Sugar sweetened beverage between meals

Sugar sweetened beverage (20% of energy requirement/day)

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

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Inclusion Criteria

* healthy

Exclusion Criteria

* regular use of medication,
* smoking,
* chronic disease,
* vegan/vegetarian diet,
* fructose intolerance,
* irregular eating behaviour (less then 3 meals/day)
Minimum Eligible Age

20 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Hohenheim

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Anja Bosy-Westphal, Prof PhD

Role: PRINCIPAL_INVESTIGATOR

University of Hohenheim, Stuttgart, Germany

Locations

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Institute of Nutritional Medicine, University of Hohenheim

Stuttgart, , Germany

Site Status

Countries

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Germany

Other Identifiers

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OrangeJuice

Identifier Type: -

Identifier Source: org_study_id

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