Effect of Anthocyanins Extracted From Purple Potatoes on Healthy Study Subjects' Postprandial Glycemia and Insulinemia

NCT ID: NCT02940080

Last Updated: 2022-03-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

18 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-10-31

Study Completion Date

2021-12-31

Brief Summary

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A randomized, single-blind cross-over clinical nutrition trial will be conducted. The effects of yellow-fleshed potatoes and yellow-fleshed potatoes supplemented with anthocyanins extracted from purple-fleshed potatoes on healthy men's postprandial glycemia and insulinemia will be compared. Additionally, the postprandial metabolism and metabolites, and the appearance and metabolism of the flavonoids and their metabolites is studied in plasma, urine and feces.

Detailed Description

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Conditions

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Postprandial Glycemia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Investigators

Study Groups

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Anthocyanins and yellow potato

168 mg of anthocyanins extracted from purple-fleshed potatoes added to 350 g of steam-cooked mashed potatoes in water

Group Type EXPERIMENTAL

Dietary

Intervention Type OTHER

Yellow potato

350 g of steam-cooked mashed potatoes in water

Group Type EXPERIMENTAL

Dietary

Intervention Type OTHER

Interventions

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Dietary

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age 18-45
* Male
* No regular medication
* No participation in a drug trial or blood donation within 2 months
* Non-smoker
* Signs informed consent
* Body mass index 18.5-27 kg/m2
* Fasting plasma cholesterol \< 5.5 mmol/l
* Fasting plasma triacylglycerols \< 2.6 mmol/l
* Fasting plasma glucose 4-6 mmol/l
* blood pressure \<140/80 mmHg
* hemoglobin\>130 g/l
* Fasting plasma alanine amino transferase (ALAT) \<60 U/l (normal liver function)
* Fasting plasma thyroid-stimulating hormone (TSH) 0.4 - 4.5 mU/l (normal thyroid function)
* Fasting plasma creatinine \<118 µmol/l (normal kidney function)

Exclusion Criteria

* Regular smoking
* Alcohol abuse
* Regular medication
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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University of Turku

OTHER

Sponsor Role lead

Responsible Party

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Kaisa Linderborg

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Kaisa M Linderborg, PhD

Role: PRINCIPAL_INVESTIGATOR

Department of Biochemistry, University of Turku

Locations

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Department of Biochemistry, University of Turku

Turku, , Finland

Site Status

Countries

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Finland

Other Identifiers

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Siniset perunat 2

Identifier Type: -

Identifier Source: org_study_id

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