Effect of Potato Fiber on Appetite and Fecal Fat Excretion

NCT ID: NCT02957318

Last Updated: 2017-09-13

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 18 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2016-09-30
• Study Completion Date: 2017-03-31

Brief Summary

Results have indicated that some dietary fibers increase fecal fat excretion and particularly viscous fibers suppress appetite sensation and reduce energy intake. Both these effects may contribute to body weight management.

Aim: The aim of the study is to investigate the potential of 3-weeks daily intake of potato pulp (FiberBind), rhamnogalacturonan I isolated potato fiber (RG-I) vs. a low-fiber control (placebo) on satiety and fecal fat excretion in healthy adults. Furthermore, a number of secondary endpoints are investigated.

Conditions

Fecal Fat Increased; Obesity; Appetite

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: CROSSOVER
• Primary Study Purpose: PREVENTION
• Blinding Strategy: SINGLE

Study Groups

FiberBind

Group Type: EXPERIMENTAL

FiberBind

Intervention Type: DIETARY_SUPPLEMENT

Potato pulp consisting of 68% fiber (5.5 soluble, 76.7% insoluble and 17.8% resistant starch), 9.7% water, 0.3% fat, 7.2% protein and 14% carbohydrates (starch).

RG-I fiber

Group Type: EXPERIMENTAL

RG-I fiber

Intervention Type: DIETARY_SUPPLEMENT

Soluble fiber extracted from potato pulp consisting of 95% fiber and 5% water.

Placebo

Group Type: PLACEBO_COMPARATOR

Placebo

Intervention Type: DIETARY_SUPPLEMENT

Low-fiber control

Interventions

FiberBind

Potato pulp consisting of 68% fiber (5.5 soluble, 76.7% insoluble and 17.8% resistant starch), 9.7% water, 0.3% fat, 7.2% protein and 14% carbohydrates (starch).

Intervention Type: DIETARY_SUPPLEMENT

RG-I fiber

Soluble fiber extracted from potato pulp consisting of 95% fiber and 5% water.

Intervention Type: DIETARY_SUPPLEMENT

Placebo

Low-fiber control

Intervention Type: DIETARY_SUPPLEMENT

Eligibility Criteria

Inclusion Criteria

• Healthy Men
• BMI between 18.5 and 27.0 kg/m2
• Age 20-40 years

Exclusion Criteria

• Intake of potatoes with main meals more frequent than 4 times per week
• Chronic diseases (known diabetes, cardiovascular disease, irritable bowels disease, colitis ulcerosa, crohn disease, or other chronic diseases which could affect the results of the present study)
• Gluten allergy
• Use of daily prescription medicine (mild analgesics are allowed)
• Use of lipid-lowering agents (e.g. Becel, HUSK)
• Use of food supplements of relevance to the study (such as pre- and probiotics)
• Irregular intake of vitamin /mineral supplements (two weeks prior to and during the entire study period)
• Smoking
• Elite athletes (>10 hours of strenuous physical activity per week)
• Blood donation (<1 month before study commencement and during study period)
• Participation in other clinical studies (<1 month before study commencement and during study period)
• Inability (physically or psychologically) to comply with the procedures required by the protocol judged by the Investigator

• Minimum Eligible Age: 20 Years
• Maximum Eligible Age: 40 Years
• Eligible Sex: MALE
• Accepts Healthy Volunteers: Yes

Sponsors

University of Copenhagen

OTHER

Sponsor Role: lead

Responsible Party

Anne Birgitte Raben

Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

University of Copenhagen, Department of Nutrition, Exercise and Sports

Copenhagen, , Denmark

Countries

Denmark

Other Identifiers

B 326

Identifier Type: -

Identifier Source: org_study_id