MRI of Infrapatellar Fat Pad in Osteoarthritis

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

121 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-10-31

Study Completion Date

2016-07-31

Brief Summary

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In this study, the investigators use the clinical documentation and imaging data of MRI to do research. Clinical subjects were divided into two groups: osteoarthritis patients and healthy controls without osteoarthritis. Differences of MRI data were studied between two groups.

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Detailed Description

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In this study, the investigators applied high precision MRI technique (with as less as a slice thickness of 0.35 mm and without inter-slice gap), and calculated not only the IPFP maximal sagittal area and IPFP volume, but also the quantitated signal, and compared the differences between healthy controls and osteoarthritis patients. This is an observational cross-sectional study without specific interventions to the subjects. MRI is a regular examination in our hospital. And all subjects are included for the reasons of osteoarthritis (need MRI) and healthy controls (pain but not osteoarthritis, also need MRI). The investigator does not assign specific interventions to the subjects of the study.

Conditions

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Osteoarthritis

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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osteoarthritis patients

3.0 Tesla Magnetic resonance imaging was analyzed. It's the documentation from the outpatients and inpatients with osteoarthritis. It's not the intervention the study applied, but the subjects' disease demands.

Magnetic resonance imaging

Intervention Type RADIATION

3.0 T Magnetic resonance imaging of knee joints. It does not harm the subjects.

healthy controls

3.0 Tesla Magnetic resonance imaging was analyzed. It's the documentation from the outpatients and inpatients without osteoarthritis. It's not the intervention the study applied, but the subjects' non-osteoarthritis knee symptom demands.

Magnetic resonance imaging

Intervention Type RADIATION

3.0 T Magnetic resonance imaging of knee joints. It does not harm the subjects.

Interventions

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Magnetic resonance imaging

3.0 T Magnetic resonance imaging of knee joints. It does not harm the subjects.

Intervention Type RADIATION

Eligibility Criteria

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Inclusion Criteria

* Patients with clinical knee osteoarthritis;
* The healthy controls who require MRI test.

Exclusion Criteria

* Contraindications to magnetic resonance imaging;
* Rheumatoid arthritis patients;
* Gout;
* Hemophilic arthritis;
* Subjects who take non-steroidal anti-inflammatory drugs (NSAIDs);
* Subjects who take lipid-lowering agents;
* Subjects who have the history of knee trauma;
* Subjects who have the history of knee operation;
* Subjects who have the disease of musculoskeletal tumor near knee;
* Subjects who have joint loose bodies.

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes