Clinical Study of Novel Diagnostic Techniques for Knee Osteoarthritis

NCT ID: NCT01359553

Last Updated: 2016-10-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

12 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-05-31

Study Completion Date

2014-05-31

Brief Summary

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The purpose of this study is to clarify the potential of intra-articular ultrasound imaging, non-invasive ultrasound imaging, quantitative MRI imaging, contrast-enhanced CT imaging and arthroscopy for diagnostics of knee osteoarthritis. All methods will be cross-correlated and compared with the arthroscopic findings.

Detailed Description

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Conditions

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Knee Osteoarthritis Knee Injuries

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Knee pain

Group with knee pain problems referred to an arthroscopy.

Intra-articular ultrasound imaging of knee joint during arthroscopy

Intervention Type OTHER

Non-invasive ultrasound imaging of knee

Intervention Type OTHER

Quantitative MRI imaging of knee

Intervention Type OTHER

Contrast-enhanced CT imaging of knee

Intervention Type OTHER

Interventions

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Intra-articular ultrasound imaging of knee joint during arthroscopy

Intervention Type OTHER

Non-invasive ultrasound imaging of knee

Intervention Type OTHER

Quantitative MRI imaging of knee

Intervention Type OTHER

Contrast-enhanced CT imaging of knee

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Kellgren-Lawrence grade = 1-3 or cartilage defect detected in MRI
* Age \>= 20 years

Exclusion Criteria

* Tumor or inflammation in the knee
* Severe general diseases
* Diabetes
Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Oulu University Hospital

OTHER

Sponsor Role collaborator

University of Eastern Finland

OTHER

Sponsor Role collaborator

Kuopio University Hospital

OTHER

Sponsor Role collaborator

University of Oulu

OTHER

Sponsor Role lead

Responsible Party

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Simo Saarakkala

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Simo Saarakkala, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

University of Oulu and Oulu University Hospital

Petri Lehenkari, M.D., Ph.D.

Role: STUDY_DIRECTOR

University of Oulu and Oulu University Hospital

Miika T Nieminen, Ph.D.

Role: STUDY_DIRECTOR

University of Oulu and Oulu University Hospital

Risto Ojala, M.D., Ph.D.

Role: STUDY_DIRECTOR

Oulu University Hospital

Locations

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Oulu University Hospital

Oulu, , Finland

Site Status

Countries

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Finland

Other Identifiers

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UltraRusto

Identifier Type: -

Identifier Source: org_study_id