Effects of Acutely Elevated Afterload on Left Ventricular Contractility and Relaxation
NCT ID: NCT02751853
Last Updated: 2022-09-10
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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TERMINATED
NA
20 participants
INTERVENTIONAL
2016-12-31
2022-08-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
DIAGNOSTIC
NONE
Study Groups
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HFPEF
Patient with heart failure with preserved ejection fraction (HFPEF)
Conductance catheter
Continuous online measurements of left ventricular pressure and volume using conductance catheters
HFREF
Patient with heart failure with reduced ejection fraction (HFREF)
Conductance catheter
Continuous online measurements of left ventricular pressure and volume using conductance catheters
No HFPEF/HFREF
Patient without heart failure with preserved ejection fraction (HFPEF) or heart failure with reduced ejection fraction (HFREF)
Conductance catheter
Continuous online measurements of left ventricular pressure and volume using conductance catheters
Interventions
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Conductance catheter
Continuous online measurements of left ventricular pressure and volume using conductance catheters
Eligibility Criteria
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Inclusion Criteria
* HFPEF (Group 1) OR HFREF (Group 2) OR absent echocardiographic evidence of HFREF OR HFPEF(Group 3)
AND
* Sinus rhythm during invasive measurements
* Age ≥18 years
* Negative pregnancy test in women with childbearing potential
* Written informed consent
Exclusion Criteria
* Acute myocardial infarction \<6 months
* Planned cardiac surgery or cardiovascular intervention within 6 months following inclusion
* Valvular heart disease \>2°
* Severe comorbidities with limited life expectancy \<12 months
* Precapillary pulmonary hypertension
* Participation in another trial
18 Years
ALL
No
Sponsors
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University of Luebeck
OTHER
Responsible Party
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Holger Thiele
Director, Department of Cardiology, Angiology, and Intensive Care Medicine, University Heart Center Luebeck
Locations
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Universitätsklinikum Schleswig-Holstein
Lübeck, Schleswig-Holstein, Germany
Countries
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Other Identifiers
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16-011
Identifier Type: -
Identifier Source: org_study_id
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