Cardiac T1 Mapping Enables Risk Prediction of LV Dysfunction After Surgery for Aortic Regurgitation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-07-01

Study Completion Date

2020-03-13

Brief Summary

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To assess whether cardiac T1 mapping for detection of myocardial fibrosis enables preoperative identification of patients at risk for early left ventricular dysfunction after surgery of aortic regurgitation.

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Detailed Description

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We hypothesized that a diffuse interstitial myocardial fibrosis may be present in AR patients who experience early systolic LV dysfunction after aortic valve surgery. We aimed to evaluate the association between preoperative cardiac T1 mapping for detection of myocardial fibrosis and early systolic LV dysfunction after surgery for aortic regurgitation.

Conditions

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Aortic Regurgitation

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients prior to aortic valve surgery

aortic valve surgery

Intervention Type PROCEDURE

Interventions

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aortic valve surgery

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Consecutive patients with severe aortic regurgitation referred for aortic valve surgery were prospectively enrolled in the study.

Exclusion Criteria

* history of coronary artery disease
* acute aortic valve disease (i.e., type A aortic dissection or infectious endocarditis)
* common contraindications for MRI such as severe obesity and metallic foreign bodies.

Eligible Sex

ALL

Accepts Healthy Volunteers

No